The reactions of these, together with those of a known 3- C-methyl epoxide ( 2), with three kinds of lithium methylcuprate were investigated. Except for 2 and 7, the vicinal monodeoxy di- C-methyl derivatives were obtained by attack of the cuprates at the sterically less-hindered site ...
The amount of NaOH consumed corresponds to the amount of hydrogen chloride released in the epoxide formation according to the reaction (Figure 5): Figure 5. Scheme for creating a reactive form of [IME]+Cl−. A total of 1 g of [IME]+Cl− commercial product and 40 mL 0.1 N NaOH ...