Antipsychotic pharmacotherapy is strongly obesogenic and is associated with increased oxidative stress in patients with schizophrenia. However, whether these changes reflect psychopathology, antipsychotic efficacy, or some other factor is not known. Our
2015. Behavioral tests and oxidative stress evaluation in mitochondria isolated from the brain and liver of mice treated with riparin A. Life Sciences, 121: 57-64.NUNES, G.B.L. et al. Behavioral tests and oxidative stress evaluation in mitochondria isolated from the brain and liver of mice ...
Inhibition of ER stress significantly reduced aldosterone/MR-induced autophagy. In addition, the activation of ER stress increased the formation of autophagy, which protected podocytes from apoptosis. Moreover, we observed that the addition of ROS scavenger, N-acetyl cystein (NAC), blocked both ER ...
Cardiovascular diseases (CVDs) have diverse physiopathological mechanisms with interconnected oxidative stress and inflammation as one of the common etiologies which result in the onset and development of atherosclerotic plaques. In this review, we illustrate this strong crosstalk between oxidative stress, i...
Oxidative Stress in Neurology and in Neurodegenerative Processes Chapter© 2020 Introduction Identifying factors that contribute to neurodegenerative processes in the brain is one of the major goals of modern medicine. Currently, there are several hypotheses concerning the mechanisms that lead to the dama...
Figure 5. Centrosome Amplification Induces an Early Stress Response that Leads to Altered Secretion (A) Left, quantification of Ki67 positive cells. Right, cells stained for Ki67. Scale bar: 40 μM. (B) Left, cells stained for β-galactosidase (blue). Right, quantification of β-galactosidase...
Moreover, it has been observed that oxidative stress regulates the expression of genes governing lipid and glucose metabolism through activation or inhibition of intracellular sensors. Diet constituents can modulate redox reactions and the oxidative stress extent, thus also acting on nuclear gene ...
To date, the influence of milk and milk fat on inflammation, oxidative stress, and cellular longevity has received little attention. Cellular longevity is often indexed objectively by measuring the length of telomeres [21,22]. Adults with short telomeres tend to have more oxidative stress and chro...
Oxidative stress-induced redistribution of the VE-cadherin/β-catenin/F-actin complex is partially prevented by BMP9/10 treatment or MMPs inhibition Since cadherin processing modifies its binding to β-catenin11, we then analysed by immunofluorescence the co-localization of VE-cadherin and β-catenin...
The topic of exercise-induced oxidative stress has received considerable attention in recent years, with close to 300 original investigations published since the early work of Dillard and colleagues in 1978. Single bouts of aerobic and anaerobic exercise can induce an acute state of oxidative stress....