oxidative stress is particularly relevant to SCI where the increased level of ROS is constantly generated for a prolonged period of time leading to progressive oxidative stress in secondary injury of SCI.18 Systematic increases in Nrf2 and ARE-driven heme oxygenase-1 in the spinal cord of SODG...
Tregcells is attributed to their weak NRF2-associated antioxidant system and high vulnerability to free oxygen species in the tumor microenvironment. Thus, the data support a model wherein tumor Tregcells sustain and amplify their suppressor capacity through inadvertent death via oxidative stress. This...
Effect of increasing temperature in oxidative stress was tested in Gobius paganellus.Lipid peroxidation, GST, SOD and catalase activities were estimated in various tissues.The levels of the oxidative stress biomarkers were always higher in the gills.Muscle presented the lower levels of all the biomar...
Deoxynivalenol Ginsenoside Rb1 Mice Oxidative Stress Apoptosis Immunotoxicity 1. Introduction Mycotoxins are the natural contaminants in some food and feedstuffs, and pose a grave threat to animal and human health worldwide (Hussein and Brasel, 2001). Deoxynivalenol (DON), also known as vomitoxin a ...
Abstract Atherosclerotic lesions initiate in regions characterized by low shear stress and reduced activity of endothelial atheroprotective molecules such as nitric oxide, which is the key molecule managing vascular homeostasis. The generation of reactive oxygen species from the vascular endothelium is strongl...
Therefore, nicorandil may be a promising candidate for protection from liver injury induced by APAP. Graphical abstractSimilar content being viewed by others Sinapic acid ameliorates paracetamol-induced acute liver injury through targeting oxidative stress and inflammation Article 13 March 2022 Diacerein...
The Bantu haplotype was correlated to a worse clinical status because of low Hb F levels and to increased oxidative stress, inflammation and DNA damage.37,38,48 On the other hand, two studies showed that the presence of the Bantu haplotype was not always correlated with a worse prognosis.27...
Oxidative stress assay The oxidative stress assay was performed as described previously [31]. Briefly, adult hermaphrodites (30 worms/group) were transferred to a 96-well plate containing M9 buffer with 3 mM H2O2. After incubation at 20 °C for the specified durations, the number of dead worm...
novacula induced a progressive increase in the markers of oxidative stress and of the immune response, as the degree of parasitism increased along with a decrease in the body condition index. The prevalence of ectoparasite infection in the Es Cubells area is very high compared to the majority ...
Target gene expression is driven forward when a nuclear accumulation of NRF2 exists; this happens when electrophiles and oxidative stress are present in cells [57]. Injuries to cells may arise from oxidative stress—an imbalance between oxidative and antioxidative events. Evidence that viral ...