The term "oxidative phosphorylation," as distinct from photosynthetic and glycolytic phosphorylation, means that the transfer of electrons (hydrogen) from the oxidizable substance to oxygen or another acceptor is effected by means of specific dehydrogenases and other enzymes forming the respiratory chain...
The final phase of cellular respiration is oxidative phosphorylation . Both the electron transport chain and chemiosmosis make up oxidative phosphorylation. During this phase of cellular respiration, all of the NADH and FADH 2 that were produced in other phases of cellular respiration (glycolysis, the...
oxidative phosphorylation Thesaurus Medical Acronyms Encyclopedia Wikipedia oxidative phosphorylation n. The process in cell metabolism by which respiratory enzymes in the mitochondria synthesize ATP from ADP and inorganic phosphate during the oxidation of NADH by molecular oxygen. ...
Oxidative phosphorylation (OXPHOS) in the mitochondrial inner membrane is a therapeutic target in many diseases. Neural stem cells (NSCs) show progress in improving mitochondrial dysfunction in the central nervous system (CNS). However, translating neural stem cell-based therapies to the clinic is cha...
The mitochondrial oxidative phosphorylation (OXPHOS) system is the final biochemical pathway in the production of ATP. The OXPHOS system consists of five multiprotein complexes, the individual subunits of which are encoded either by the mitochondrial or by the nuclear genome. Defects in the OXPHOS sy...
In hypertension, oxidative stress promotes posttranslational modification (oxidation and phosphorylation) of proteins and aberrant signalling with consequent cell and tissue damage. Many enzymatic systems generate ROS, but NADPH oxidases (Nox) are the major sources in cells of the heart, vessels, ...
During oxidative phosphorylation, the mitochondria generate reactive oxygen species (ROS) and ‘free radicals.’ The production of ROS can be influenced by calorie intake and other nutritional variables, as well as energetic demands and environmental stress (Loeb et al., 2005; Wallace, 2008). ...
Shoffner JM. Oxidative phosphorylation disease: diagnosis and pathogenesis. In: Berdainer CD (eds) Mitochondria in Health and Disease. Taylor & Francis, Boca Raton, 2005; pp. 247–300 ChapterGoogle Scholar Tengan CH, Gabbai AA, Shanske S, Zeviani M, Moraes CT. Oxidative phosphorylation dysfunct...
Toward this end, and based on our previous work demonstrating the metabolic differences that exist between PaCSCs and non-PaCSCs, we describe herein a long-term and sustained cell culture system enriched in PaCSCs based on forced oxidative phosphorylation (OXPHOS), defined by electron transport ...
Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation Zhixin Li, Kathy Nga-Chu Lui, Sin-Ting Lau, Frank Pui-Ling Lai, Peng Li, Patrick Ho-Yu Chung, Kenneth Kak-Yuen Wong, Paul Kwong-Hing Tam, Maria-Mercedes ...