Cancer cells exhibit enhanced lactate production to satisfy biosynthetic adenosine triphosphate requirements and also supply ribose 5‐phosphate (R5P) and nicotinamide adenine dinucleotide phosphate via the pentose phosphate pathway (PPP). Yet, little is known about the mechanism by which glycolytic flux ...
we show that the oxidative pentose phosphate pathway (oxPPP) in endothelial cells is required for establishing vMC coverage of the dorsal aorta during early vertebrate development in zebrafish and mice. We demonstrate that laminar shear stress and blood flow maintain oxPPP activity, which in turn,...
单词 Oxidative Pentose Phosphate Pathway 释义 SeeOPPP 随便看 Theatre of the Stars Theatre of Work Enabling Relationships Theatre Ontario Theatre Owners and Bookers Association Theatre Pipe Organ Theatre Provided Equipment Refurbishment Theatre Students' Association Theatrical theatrical Theatrical Management ...
上海市免疫学研究所李斌研究员课题组和复旦大学附属华山医院/脑科学转化研究院杨辉研究员,在Nature Metabolism杂志在线发表题为 Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics 的研究论文,揭示非氧化磷酸戊糖途径(非氧化PPP)对调节性T(Treg)细胞...
Cytosolic NADP is recycled to NADPH by the oxidative pentose-phosphate pathway (oxPPP), malic enzyme 1 (ME1) and isocitrate dehydrogenase 1 (IDH1). Here we show that any one of these routes can support cell growth, but the oxPPP is uniquely required to maintain a normal NADPH/NADP ratio,...
In time-resolved metabolomics experiments, we observed that within seconds after stress induction, glucose catabolism is routed to the oxidative pentose phosphate pathway (PPP) and nucleotide synthesis independent of previously postulated blocks in glycolysis (i.e., of GAPDH or PKM2). Through ultra-...
The first portion of the pentose phosphate pathway involves the oxidation of glucose in three steps, with the concomitant production of NADPH. The first step in the pentose phosphate pathway is catalyzed by glucose-6-phosphate dehydrogenase. In normal red blood cells, the NADPH produced by glucose...
The oxidative pentose phosphate pathway (OPPP), catalyzing the oxidation of glucose-6-phosphate to ribulose-5-phosphate is ubiquitous in eukarya and bacteria but has not yet been reported in archaea. In haloarchaea a putative 6-phosphogluconate dehydrogenase (6PGDH) is annotated, whereas a gene ...
必应词典为您提供oxidative-pentose-phosphate-pathway的释义,网络释义: 氧化戊糖磷酸途径;氧化性磷酸五碳糖路径;
摘要: Heartwood formation is characterized by an increase in the activity of the oxidative pentose phosphate pathway and a shift in the pyridine nucleotide pool towards tri-phospho-pyridine nucleotides.关键词: Acer pseudoplatanus L Glucose-6-phosphate dehydrogenase Heartwood formation Oxidative pentose ...