In the presence of potassium hydroxide and potassium iodide, more stable enolate is formed from the ketone and this reacts with the electrochemically generated iodine. The electrochemical oxidation of aldehydes to the carboxylic acid, catalyzed by bromide or iodide ions, is an extensively exploited ...
To improve the efficiency and applicability of biocatalytic redox-reactions for asymmetric ketone-reduction and enantioselective alcohol-oxidation catalyze... W Kroutil,H Mang,K Edegger,... - 《Current Opinion in Chemical Biology》 被引量: 526发表: 2004年 Selenium dioxide oxidation of ketones and ...
Inketone: Reactions of ketones Secondary alcohols are easily oxidized to ketones (R2CHOH → R2CO). The reaction can be halted at the ketone stage because ketones are generally resistant to further oxidation. Oxidation of a secondary alcohol to a ketone can be accomplished by many oxidizing agent...
V. The Oxidation of Ketones to Esters1 Peroxytrifluoroacetic acid has been found to oxidize ketones to esters in excellent yields. A noteworthy application of this reaction is the oxidation of methyl cyclopropyl ketone to cyclopropyl acetate in 53% yield....
The favorable route was as follows: 2-phenoxy-1-phenylethanol (β–O–4 motif) becomes dehydrogenated to 2-phenoxy-1-phenylethanone (oxidized β–O–4 motif); this ketone motif will tautomerize to its enol (2-phenoxy-1-phenylethenol), which will again be dehydrogenated at the position of...
Reactions of aldehydes and ketones: oxidation reduction nucleophilic addition 1) Aldehydes are easily oxidized, ketones are not. 2) Aldehydes are more reactive in nucleophilic additions than ketones. alkane alcohol aldehyde ketone carboxylic acid oxidation reduction reduction addition product nucleophilic addi...
;SOLUTION: An oxide (ketone, alcohol, carboxylic acid or the like) is obtained by oxidizing a substrate (cycloalkanes, polycyclic hydrocarbons, aromatic compounds having methyl group) with oxygen in the presence of the oxide catalyst system, which is composed of an imide compound (N-hydroxy ph...
Miscellaneous Substrates Oxidative Decarboxylations of Aldehydes Oxidations of Ketones Ketone Cleavage Reactions Simple Acyclic Ketones Simple Cyclic Ketones Functionalized Ketones Oxidative Rearrangements of Ketones Baeyer-Villiger Reactions Ketone Amidations Miscellaneous Rearrangements Willgerodt Reactions Conclusions ...
Therefore, this approach had to be abandoned. The modified route, outlined in Scheme 27, began with transformation of the aldehyde 124 into ketone 125 using a two-step procedure, formation of TIPS-protected enol 125 and oxidative cleavage of the double bond, to form 126 in 87% yield. This...
Applicants have developed a process for the oxidation of ketones to esters. The process involves contacting the ketone with hydrogen peroxide and a catalyst at oxidation conditions. The catalyst is a