Here, we present the first systematic benchmark of computational methods for detection of DNA 5mCs for nanopore sequencing at the human whole-genome scale. We assess the impact of CpG locations on detection accuracy using nanopore sequencing data generated from human cell lines and primary leukemia ...
Journal on Bioinformatics and Biotechnology (2011) The amino propeptide of collagen a1(XI) (NPP) has been shown to bind glycosaminoglycans and to form a dimer. While these are independent biochemical events, it is likely that dimerization facilitates the interaction with glycosaminoglycans or ... ...
Bioinformatics 25, 1966–1967, doi:10.1093/bioinformatics/btp336 (2009). 27. Kopylova, E., Noe, L. & Touzet, H. SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data. Bioinformatics 28, 3211–3217, doi:10.1093/bioinformatics/bts611 (2012). 28. Noguchi, H., ...
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What will this mean for structural bioinformatics? It means we can focus on other problems beyond structural prediction. Because that is what AlphaFold 2 has solved and not, as many press releases have claimed, theprotein folding problem. DeepMind’s cod...
ImpactFactorstakenfromthe2012JournalCitationReports(ThomsonReuters2013) ActaBiochimicaetBiophysicaSinica-1.807 AlcoholandAlcoholism-1.956 AnnalsofBotany-3.449 AnnalsofOccupationalHygiene,The-2.157 BehavioralEcology-3.216 Bioinformatics-5.323 BioScience Brain-9.915 Brie ngsinBioinformatics-5.298 Brie ngsinFunctional...
Impact of the gap closing procedure on the JN3 assembly The JN3 assembly was gap closed using PBJelly and we detected several duplicated regions of several Kb in this gap-closed assembly that were not present in the previous assembly. We first detected tandemly duplicated genes using Blast and ...