followingthreemonthsinthewholegroupandthetwosubgroups(P>0.05).Theincidencerateofsideeffectsduetothetherapywas19.40%(13of67).Thesideeffectsweremainlyfoundinthefirstthreemonths.ItisconcludedthatOXCisthefirst-lineanti-epilepticdrug(AED) forpartialseizures,and couldbeused asthemonotherapyandadd-ontherapyfornewly di...
Explore the full scope of our drug knowledge tailored for pharmaceutical research needs in our data library. Learn more. Structure Description A medication used to treat certain seizure disorders. DrugBank ID DB00776 Type Small Molecule US Approved YES Other Approved YES Patents 14 Indicated Conditio...
96% of a radiolabelled dose of oxcarbazepine can be found in the urine, but < 1% appears as unchanged drug. The value of monitoring plasma concentrations ofdoi:10.2165/00003495-199243060-00007Susan M. GrantDiana FauldsSpringer International PublishingDrugs...
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multi-organ hypersensitivity, has occurred with oxcarbazepine. Some of these events have been fatal or life-threatening. DRESS typically, although not exclusively, presents with fever, rash, lymphadenopathy and/or facial swell...
{SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Novartis, O 安全信息 RTECSHN8445000 WGK Germany3 Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter TYPE OF TEST : TDLo - Lo...
Oxcarbazepine Metabolite reagents are specific drug testing reagents utilized in the determination of cluster of medical conditions which includes epilepsy, bipolar disorders, seizures and others. The oxcarbazepine metabolite reagents are utilized in determining levels of metabolite and an important measure in...
P-glycoprotein (P-gp) is an efflux transporter involved in drug-resistant epilepsy and some flavonoids have been targeted as effective P-gp inhibitors. Herein, we assessed the impact of silymarin on the pharmacokinetics of three antiepileptic drugs (AEDs) in rats. Animals were pretreated with sily...
Due to the small numbers, it was not possible to analyse the different types of surgical procedures individually. Outcomes after any type of surgery were better on all evaluations and eight patients felt that they should have had surgery earlier. Oxcarbazepine is a potent antineuralgic drug with ...
Due to the small numbers, it was not possible to analyse the different types of surgical procedures individually. Outcomes after any type of surgery were better on all evaluations and eight patients felt that they should have had surgery earlier.Oxcarbazepine is a potent antineuralgic drug with ...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the severe cutaneous adverse drug reactions that are potentially life threatening. The strong association between the HLA-B*1502 allele and carbamazepine-induced SJS (CBZ-SJS) has been documented in Han Chinese in one...