This study introduces oxadiazolines as innovative and complementary photoactivatable labels for addition to the toolbox and demonstrates their application in vitro and through in cellulo labeling experiments. Oxadiazolines can be easily synthesized from ketone moieties and cleaved with 302–330 nm light ...
Oxadiazolines can be easily synthesized from ketone moieties and cleaved with 302–330 nm light to cleanly liberate a diazo reactive moiety that can covalently modify nucleophilic amino acid residues. Notably, oxadiazolines are compatible with various organic reaction conditions and functional groups, ...
Diastereo‐ and Enantioselective Synthesis of Δ2‐1,2,4‐Oxadiazolines by 1,3‐Dipolar Cycloaddition of Nitrile Oxides with Chiral Hydrazones. Research devoted to the synthesis of highly substituted prolines, which are hepatitisC virus inhibitors, using 1,3-dipolar cycloadditions (1,3-DC) of az...
diaryloxyoxadiazolineacétal du cétèneorthoformiateSymmetric and unsymmetric 2,2-diaryloxy-5,5-dimethyl--1,3,4-oxadiazolines were synthesized by oxidative cyclization of aryloxycarbonyl hydrazones of acetone with lead tetraacetate and subsequent treatment of the product mixture with a phenol in ...
The novel 5-oxo-4-trisubstituted tin-1,3,4-oxadiazolines of the present invention have the general formula: ##STR3## wherein R is aryl of 6 to 10 carbon atoms; substituted aryl substituted with 1 to 5 substituents selected from halogen, nitro, lower alkyl of 1 to 6 carbon atoms, low...
ChemInform Abstract: Spiro-Fused 2-Alkoxy-2-amino-Δ3-1,3,4-oxadiazolines. Synthesis and Thermolysis to Corresponding Aminooxycarbenesdoi:10.1002/chin.199810152oxadiazole derivativescleavage reactions, decomposition reactions, pyrolysisintermediates (and their reactions)...
ChemInform Abstract: Diastereo- and Enantioselective Synthesis of Δ2-1,2,4-Oxadiazolines by 1,3-Dipolar Cycloaddition of Nitrile Oxides with Chiral HydrazonesChemInform Abstract: Diastereo- and Enantioselective Synthesis of Δ2-1,2,4-Oxadiazolines by 1,3-Dipolar Cycloaddition of Nitrile Oxides with...
Then 2a～2j respectively were cyclodehydrated with propanoic anhydride to afford3-N-propanoyl-1,3,4-oxadiazolines(3a～3j). 4-甲氧基苯甲酰肼(1)与芳醛反应得到相应的酰腙(2a~2j),2a~2j分别与丙酸酐脱水环化成了3-N-丙酰基-1,3,4-唑啉类化合物(3a~3j),通过元素分析I、R1、HNMR和MS对化合物...
contng. (I). Prepn. of (I). (I) X = halogen, alkyl, alkenyl, or haloalkyl, or NO2. Pesticides and partic. herbicides. Fungicides and insecticides. Application rates of 2-4 lb./acre (I) control many types of weeds while being non-toxic to plants such as rice.JOHN KRENZER...
The synthesized 1,3,4-oxadiazolines were screened for in vitro for their biological activity against a variety of bacterial strains (Euterococci, Escherichia coli, Staphylococcus aureus, Klebsiella spp, Proteus spp, and fungi (Aspergillus niger, Candida albicans), employing the nutrient agar disc ...