The rapid and extraordinary development and deployment of Coronavirus disease 2019 (COVID-19) vaccines worldwide represent an unprecedented achievement in the history of vaccine development. This chapter provides an overview of COVID-19 vaccine strategies, platforms, clinical trials, and regulatory ...
Vaccines are important preventive measures against severe COVID-19 disease, hospitalization, death, and persistent symptoms (ie, long COVID). The FDA Vaccines and Related Biological Products Advisory Committee (VRBPAC) continues to assess the optimal composition of COVID-19 primary and booster vacc...
There's no way to tell how long the pandemic will continue. There are many factors, including the public's efforts to slow the spread, researchers' work to learn more about the virus, their search for a treatment, and the success of the vaccines. Symptoms of COVID-19 The main symptoms ...
Due to the transmission of COVID-19 through airborne droplets, the transmission of SARS-CoV-2 is high in closed environments without ventilation even with social distancing. In general, according to past experiences, in the absence of medical measures (drug prescriptions and vaccines), to manage ...
COVID-19is one of the most grievous pandemics of modern human history. As of 20 months post-outbreak, SARS-CoV-2 has globally infected more than 200 million people causing over 4 million deaths (https://coronavirus.jhu.edu/map.html). A few vaccines have been authorized for emergency usage...
of COVID-19 pathogenesis is crucial in providing the scientific rationale necessary to develop anti-COVID19 drugs and vaccines. According to the most recently published literature, COVID-19 pathogenesis was postulated to occur in three sequential phases: pulmonary, proinflammatory, and prothrombic. ...
resulting in higher risks of COVID-19 breakthrough infections57and breakthrough infections in fully vaccinated patients.58Vaccines may reduce breakthrough infections significantly, and United Kingdom data59indicated that fully vaccinated patients were at a reduced risk for severe complications, break...
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However, the pathophysiology of acute and post-acute manifestations of COVID-19 (long COVID-19) is understudied. Endothelial cells are sentinels lining the innermost layer of blood vessel that...
Numerous clinical trials have been prioritized globally for testing new vaccines and treatments against this disease. This review provides a broad insight into different aspects of COVID-19, an introduction to SARS-CoV-2 mitigation strategies and the present status of diagnostics and therapeutics....
classified as antiviral agents, biologic agents, anti-inflammatory agents, and herbal agents. Besides the discovered therapeutic agents, vaccines are also in preclinical and clinical trials. This review focuses on the potential treatments that have been employed up to now in treatment of COVID-19 ...