Cell signaling: an overview. Oncogene. 1998; 17 :1329–1330.N Dhanasekaran (1998) Cell signaling: An overview. Oncogene 17: 1329-1330. :Dhanasekaran, N. (1998) Cell signaling: an overview. Oncogene 17: pp. 1329-1330Dhanasekaran N.Cell Signaling: An overview. Oncegene . 1998...
The Alliance for Cellular Signaling is a large-scale collaboration designed to answer global questions about signalling networks. Pathways will be studied intensively in two cells — B lymphocytes (the cells of the immune system) and cardiac myocytes —
Cell viability is a measure of the proportion of live, healthy cells within a population. Assays to assess cell viability measure metabolic activity, ATP content, cell proliferation, or membrane integrity.
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
Cell-to-cell communication between cancer cells and cells in the bone/BM niche is essential for the survival and growth of tumor cells in bone. The Notch signaling pathway is activated by cell-to-cell contact between adjacent cells and regulates proliferation, apoptosis, and differentiation in mul...
Glycerophospholipids are ubiquitous in nature and are crucial components of the cell phospholipid bilayer, constituting around 80% of total membrane lipids, as well as being implicated in the metabolism of cell signaling. They are amphiphilic molecules, characterized by acyl chains and glycerol (as ...
Macrophages also function in the presentation of antigens to T cells, as well as in the induction of expression of co-stimulatory molecules on other antigen-presenting cell types, which initiates the adaptive immune response [1]. Furthermore they play an important role...
In order to attain unchecked proliferative capability, cancer cells rely on the inactivation of several key players of cell cycle progression, as well as extracellular matrix (ECM) components that act as antagonists to growth signaling pathways. To achieve ...
Cell Lineage A.D.Chisholm, inBrenner's Encyclopedia of Genetics (Second Edition), 2001 Overview of Biology of Cell Lineages History of Cell Lineage Studies Celllineagestudies began with Whitman’s description of cleavage patterns in leech embryos in the 1870s, and continued with descriptions ofline...
of the molecular basis ofhuman geneticdisorders and cancer. For example, many genetic diseases have been discovered as a result of a single mutation or a specificchromosomal rearrangementand are understood at the molecular level, including, but not limited to, sickle-cell anemia,hemophilia,cystic ...