Overly fast correction of hyponatremia is the most important risk factor for osmotic demyelination, which can result in severe neurologic deficits and mortality.1 Despite widespread awareness of the problem, overcorrection of hyponatremia still occurs. Because the most common reason is the development of...
Rapid correction of hyponatremia can also lead to serious complications. The development of V2 antagonists, such as tolvaptan, has changed and simplified the management of dilutional hyponatremia by allowing the targeting of antidiuretic hormone (ADH) action and blocking its effect on the V2 receptor...