Where does DNA replication take place in humans? Explanation: In humans, DNA is found in the nucleus of cell. The process of replication (which copies DNA) must take place in the nucleus since this is where the DNA is found. What is the final product of translation? The amino acid seque...
In the first major single-cell co-expression analysis, Dr. Gillis and colleagues examined single-cell RNA-seq data from 31 studies, including 163 different cell types, to characterize co-expression replicability. “Surprisingly, we found that one of the ways genes interact in cells is not very ...
correlation between mRNA and GMNN protein expression was weaker, relative to FOXJ1 expression. While this difference was slight, it may have contributed to the result. Dissimilar mRNA and protein abundances may be reflective of the translation rate, its modulation, delays in protein synthesis and tr...
Spermatogenesis is a developmental process, which occurs within the seminiferous tubule of the testes and is regulated by an enormous number of proteins. In the seminiferous tubule of the testis, spermatogenic cells are in constant communication with the Sertoli cells, and this interaction is essentia...
protein and RNA synthesis, and cell elongation which leads to radicle protrusion, may not necessarily be linked together and are possibly regulated by different control mechanisms. Moreover, when seeds or embryos are grown in abscisic acid + fusicoccin, protein synthesis is considerable, cell ...
The research process is shown in Fig. 1. Table 1 Basic clinical information for the four cohorts Full size table Fig. 1 Flow chart of analysis Full size image Construction of prognostic model Univariate Cox proportional hazard analysis was carried out in TCGA-BLCA, GSE13507, GSE32548, and ...
The p110 protein is constitutively expressed and the p150 form is induced by IFN. While p110 is localized to the nucleus, p150 undergoes nucleocytoplasmic shuffling. Both ADAR1 isoforms share a Zβ domain that is not known to bind nucleic acids, three downstream double-stranded RNA-binding ...
Um, uh, and so it’s just a, a layering of information. Um, in a way that we, uh, we, that really challenges what’s called the central dogma of biology, where one stretch of DNA leads to one messenger RNA leads to one protein. That’s what we were all taught in high school ...
Prognostic and immunological values of SKA3 for overall survival in lung adenocarcinoma and its RNA binding protein involved mechanismsView further author informationhttps://orcid.org/0000-0001-9258-747513605106656@163.comChangpeng SunView further author information...
Tumor progression locus 2 (Tpl2) is a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family of serine/threonine kinases. Deletion of the Tpl2 gene is associated with a significantly higher number of papillomas and cutaneous squamous