The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The protein may bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'. Defects in OTX2 are the cause of microphthalmia syndromic...
OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endoderm...
OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endoderm...
While O-GlcNAcylation has been shown to impact the autophagic process directly,26,27 TG treatment did not directly affect the level of the autophagy marker LC3-II (Figure S3B), suggesting that TG acted on OTX2 in a targeted manner. Finally, further OTX2 stabilization was seen when combining...
Here, we report the identification of a cis-regulatory module (CRM) for the thyroid hormone receptor beta (Thrb) gene, an early cone marker. We found that ThrbCRM1 is active in progenitor cells biased to the production of cones and an interneuronal cell type, the horizontal cell (HC). ...
| bionexus protein marker | biontex | bioo scientific | biooscientific | biopioneer | biopioneerinc | bioplastics | bioporto | bioprocessing | bioprocessing inc | bioproductsmd | bioptechs | bioptic | bio-quant | bio-quant inc. | bio-rad伯乐 | biorbyt | bioreba | bioreclamationivt | Bior...
PROTEIN expressionNEUROBLASTOMAObjectives: Neuroblastoma is the most common extracranial solid tumor in childhood. YAP (Yes‐associated protein) is a highly expressed protein in NB. Nestin is an important marker of neuronal differentiation in NB. Orthodenticle homeobox (OTX) is a transcription ...
OMP / Olfactory marker 蛋白 抗體, 兔多抗ELISA 400 µg STMN1 / Stathmin 1 抗體, 兔多抗, 抗原親和純化ELISA WB IHC-P 50 µg TPK1 抗體, 兔多抗, 抗原親和純化ELISA 50 µg PVALB 抗體, 兔多抗ELISA 400 µg ADPRH 抗體, 兔多抗, 抗原親和純化WB IP 50 µg ACOT13 抗體, 兔多抗...
Utilizing TLE as a tissue-specific CRM marker, we were able to identify type I and type II CRMs (Fig. 5a,b) that activate or repress a large battery of genes, including head organizer and trunk genes (Figs 6 and 7). We estimated the number of Otx2 target genes that have type I, ...
To validate these results, we conducted ChIP-qPCR to examine the distribution of the repressive marker H3K9me3 on the OTX2 promoter region. Eleven pairs of primers were designed to detect possibly altered sites in the OTX2 promoter region. The ChIP-qPCR assay demonstrated a significantly increase...