The article discusses the development of new otoprotective drugs and agents through the Investigational New Drug application process put in place by the FDA. Research is currently being carried out in noise-induced hearing loss and tinnitus, cisplatin-induced hearing loss and tinnitus, and ...
The article discusses the development of new otoprotective drugs and agents through the Investigational New Drug application process put in place by the FDA. Research is currently being carried out in noise-induced hearing loss ...
These compounds are suitable as co-medicaments for the prevention and/or treatment of drug-induced neurotoxic effects in general and neurotoxic side effects during cancer treatments with cytostatic drugs such as platinum-derivatives, e.g. cis-, carbo- and oxaliplatin, taxanes, bleomycin, ...
In conclusion, DPOAE seems to be an appropriate tool in assessing minute changes in the cochlea after antioxidant drugs administration.doi:10.1007/s12070-014-0721-7Afsaneh DoostiYones LotfiAbdollah MoosaviEnayatollah BakhshiAzita Hajhossein Talasaz...
CISPLATINHEARING disordersANTINEOPLASTIC agentsHearing loss is one of the most common sensory disorders in humans, and a large number of cases are due to ear cell damage caused by ototoxic drugs including anticancer agents, such as cisplatin. The recent literature reported that hearing loss is ...
These drugs save the lives of millions of people around the world, but they also could cause ototoxicity. Kanamycin is an aminoglycoside antibiotic that causes loss or damage of Hair Cell receptors in the inner ear, resulting in hearing loss. The megalin is an endocytic receptor for ...