This is possibly true of pure forms, but is a harder position to sustain for the many mixed cases that we see every day. A second proposition offered is that different dementia subtypes are “caused” by dysregulation of specific neuronal proteins. Thus disorders like AD, characterized as ...
It not only validates BET protein degradation as a promising clinical strategy for anti-metastatic CRPC, but also demonstrates the feasibility of using PROTACs to treat small tumor-mediated protein-degrading solid tumor malignancies. The dysregulation of BET protein, especially BRD4, is closely related...
III. Self-Worth Dysregulation DysphoriaThe narcissist reacts with depression to criticism or disagreement, especially from a trusted and long-term Source of Narcissistic Supply. He fears the imminent loss of the source and the damage to his own, fragile, mental balance. The narcissist also resent...
Anxiety was found to be the most prevalent of all specified SEB difficulties for children with DLD, along- side insistence on sameness and emotion dysregulation; all of which shared significant correlations. Further- more, the relationship between DLD diagnosis and anx- iety was found to be ...
This paper shows two important discoveries. First,bifidobacteria(an important commensal gut bacteria) actually impacts the serotonergic system. In other words, it impacts your ability to make serotonin, the primary neurotransmitter associated with depression. Secondly, imbalances in gut microflora alone can...
Borderline Personality Disorder and Emotion Dysregulation volume 7, Article number: 17 (2020) Cite this article 6281 Accesses 19 Citations 11 Altmetric Metrics details Abstract Background Family and friends (‘carers’) of adults with borderline personality disorder (BPD) and carers of young people ...
aWords can not interpret the sadness spread throughout the body 词不可能解释悲伤被传播在身体中[translate] aThe results provide strong evidence for convergent molecular abnormalities in ASD, and implicate transcriptional and splicing dysregulation as underlying mechanisms of neuronal dysfunction in this diso...
our mother's womb bathed in our own urine. This may come as a shock to many but nevertheless is true — in the second half of pregnancy, the amniotic fluid mostly consists of the fetus' own urine which is excreted into the amniotic sac. In other words, our own urine helped us to ...
not been completely elucidated, TS is thought to be caused by “microscopical and macroscopical abnormalities within the cortico-striatal-thalamo-cortical” (CSTC) loops and, rather than being a disorder of any particular brain region, arises from dysregulation in the CSTC circuitry (Ganos, 2016)...
heart attack, suffocation, carbon monoxide poisoning, trauma, pulmonary dysfunction and the like; decreased blood flow, e.g., from occlusion, atherosclerosis, diabetic microvascular insufficiency and the like; dysregulation of nitric oxide; dysfunction of the endothelium or vascular smooth muscle; and ...