Shotgun metagenomic analyses have shown that biotin metabolism, glycan degradation, and the biosynthesis of phenylalanine, tyrosine, and tryptophan are decreased in PD68,73. High fecal concentrations of branched-chain and aromatic amino acids in PD patients are associated with an increased abundance of...
Praus, R., and Brettschneider, I., 1970, Presence of a non-sulphated glucosaminoglycan in embryonic cornea, FEBS Lett. 6: 221. Google Scholar Praus, R., and Brettschneider, I., 1971, Glycosaminoglycans in the developing chicken cornea, Ophthalmol. Res. 2: 367. Google Scholar Preston...
developed a heparin-mimetic PA (hmPA, Figure 4), designed to display the angiogenesis-promoting properties of heparin, without the need to add this glucosaminoglycan, or exogenous growth factors; their working hypothesis was confirmed, as hmPA was able, by itself, to promote angiogenesis and ...
Administration of 1000–1500 mg/day D-Chiro-Inositol (DCIns) or a combination of Myo-Inositol (MyoIns) and DCIns in their plasma molar ratio (40:1) for three or more months are among recommended treatments for metabolic syndrome and/or Polycystic Ovary S
In this work, a glycan chip is developed by introducing a pH-responsive i-motif DNA linker to control the immobilization and isolation of glycans on chip surfaces in a pH-dependent manner. On-chip enzymatic glycosylations are optimized for uniform biosynthesis of cancer-associated Globo H ...
MPO functions as a homo-dimeric glycoprotein with an average mass of 140–155 kDa. The MPO biosynthesis process is complex and includes several processing steps: proteolytic events, heme addition, N-glycan additions and dimerization [[2], [3], [4]]. It is originally translated as prepro...
(betaglycan, 300kDa) Vascular endothelial growth factor Vascular endothelial growth factor C X66087 NM_006206 X16323 NM_003029 NM_006265 NM_004346 AK098750 NM_005544 NM_004073 NM_002592 X12830 NM_002133 NM_004864 AF073310 v-myb myeloblastosis viral oncogene homolog (avian)-like 1 Platelet-...
SLC35B2 is involved in in coordinated transcriptional regulation during induction of sialyl sulfo-Lex glycan biosynthesis during acute inflammation (Huopaniemi et al., 2004) and in the sulfation of the 6-sulfolactosamine epitope in a human colorectal carcinoma cell line (Kamiyama et al., 2006)....
2.The peptide of claim 1, wherein said peptide has the ability to bind to an MHC class-I molecule, and wherein said peptide, when bound to said MHC, is capable of being recognized by CD8 T cells. 3.The peptide of claim 1, wherein the pharmaceutically acceptable salt is chloride salt...
inflammatory effects depend on (1) the presence of the sialic acid residue in the glycan headgroup of GM1 and (2) the presence of a lipid tail. We further show that several other gangliosides, but not all, share anti-inflammatory properties with GM1. In line with the effects of ...