OBJECTIVE:Human papillomavirus (HPV) 16/18 genotyping is an effective method for triage of high-risk (hr) HPV-positive women in primary hrHPV screening for cervical cancer. The present study aimed to evaluate whether co-infected with other hrHPV types will affect the risk of cervical carcinogene...
Aim Persistent infection with 1 of 14 high-risk genotypes human papillomavirus (HPV) genotypes is the crucial for the development of high-grade cervical cancer precursors. The reassuring management of women with cytology negative, high-risk HPV (HrHPV) positive is important especially after the ...
Multiple HPV infections are not uncommon, as they were found in approximately 5-10% of HPV-positive samples. The most frequently observed HPV type was HPV 16 and it is mostly associated with high-grade cervical epithelial lesions independently of patient's age. So, HPV 16 can be considered ...
To the best of our knowledge, the present study is the first to elucidate the significance of cytology and high-risk human papillomavirus (hrHPV) status in... M Sakai,T Ohara,H Suzuki,... - 《Oncology Letters》 被引量: 0发表: 2023年 The Prevalence of High Grade Cervical Intraepithelial...
Figure 1 shows the age-specific prevalence of HPV in 1,244 women (i.e. all of the women for whom a valid HPV result was obtained), 298 of whom were HPV-positive, classified into: (i) HPV 16/18; (ii) any HR; (iii) any LR; and (iv) any HPV genotype. Prevalence decreased from...
The usual recommendation for referring women with ASC-H for colposcopy is not altered by a positive triage test, whatever test is used. A negative hrHPV DNA or p16INK4a test may allow repeat testing, but this recommendation will depend on local decision thresholds for referral. Cancer Cyto...
aThrough the use of an immediate colposcopy threshold of ASC-US or worse for HR-HPV positive women and the use of a raised threshold of low-grade squamous intraepithelial lesion (LSIL) or worse for HR-HPV negative women, LBC and HR-HPV cotesting could provide the same effectiveness as LBC...
Kenny SL et al (2012) Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-beta. Am J Surg Pathol 36(6):799–807 ...
HIV-positive; have had multiple sexual partners; have sex with partners who have had multiple sexual partners; participate in high-risk sexual activity; have not been vaccinated against HPV; have a coinfection involving other sexually transmitted diseases; smoke; engage in long-term use of oral ...
ATM-activated AKT phosphorylates ACLY at S455 and increases the catalytic activity of ACLY, resulting in acetylation of histone H4K16 flanking DSB regions, which promotes the exclusion of 53BP1 and the recruitment of BRCA1, thereby promoting HR repair (Figure 2D, right) (Sivanand et al., ...