Finally, local administration of OSU6162 into the nucleus accumbens core, but not dorsolateral striatum, selectively reduced cue-controlled sucrose seeking. In conclusion, the present results show that OSU6162 reduces binge-like eating behavior and attenuates the impact of cues on seeking of palatable...
While very effective in pre-clinical studies, the United States Food and Drug Administration has terminated the clini- cal trial investigating the use of ERMAs, such as 2-deoxyglu- cose (2-DG), in prostate cancer (NCT00633087) due to serious side effects[7]. Therefore, new ERMAs with ...
Introduction: Venetoclax (VEN), a selective BCL2 inhibitor, in combination with hypomethylating agents (HMA) or low-dose cytarabine is currently the standard of care for first line treatment of older/unfit patients with acute myeloid leukemia (AML). This, however, requires indefinite cycles of t...
Advise patients that in the event of a missed daily dose of REZUROCK, it should be taken as soon as possible on the same day with a return to the normal schedule the following day. Patients should not take extra doses to make up the missed dose [seeDOSAGE AND ADMINISTRATION]. Drug In...
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