doi:10.1038/nrrheum.2016.6Liesbet LiebenNat Rev RheumatolNature Reviews RheumatologyLieben, L. Osteoarthritis: Osteophyte formation involves PAR2. Nat. Rev. Rheumatol. 2016, 12, 70-71. [CrossRef] [PubMed]
网络骨刺形成;骨赘;骨折癒合后骨块的增生
Fig. 2. Osteophyte formation in experimental murine OA (medial tibia). Cells in the synovial lining are stimulated to proliferate (b and c). Cells inside the developing osteophyte undergo chondrogenesis and deposit matrix molecules such as aggrecan (d). The most central chondrocytes further differen...
Osteophyte formation in osteoarthritis. 来自 Semantic Scholar 喜欢 0 阅读量: 6 作者: WBV Denberg 摘要: OBJECTIVE: RNA-binding protein with multiple splicing (RBPMS) has been shown to physically interact with Smads and enhance transforming growth factor-beta (TGF-beta)-mediated Smad2/3 ...
Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage. Ann Rheum Dis 2015;74:1257-64.Blaney Davidson EN, Vitters EL, Bennink MB, et al. Induc- ible chondrocyte-specific ...
Osteophytes, ie, bony outgrowths that limit joint movement and cause pain, are a hallmark of (secondary) osteoarthritis (OA), but how their formation is regulated is still unclear. Bone morphogenetic protein 2 (BMP2) has been implicated as an important mediator of osteophyte formation. When we...
[The natural course of osteoarthritis of the hip. Indication of conservative treatment in relation to osteophyte formation at the acetabular rim] [The natural course of osteoarthritis of the hip. Indication of conservative treatment in relation to the osteophyte formation at the acetabular rim]. .....
英文: Increased loading of bone stimulates bone remodeling and new bone deposition, manifested by marginal osteophyte formation and sclerosis within the overloaded subchondral bone incite a chronic inflammatory response Replacement of nercrotic bone by fibrous 中文: 过度负荷的软骨下骨质中的细微骨折激起慢...
Define osteophyte. osteophyte synonyms, osteophyte pronunciation, osteophyte translation, English dictionary definition of osteophyte. n. See bone spur. os′te·o·phyt′ic adj. American Heritage® Dictionary of the English Language, Fifth Edition. Cop
Define Osteophytes. Osteophytes synonyms, Osteophytes pronunciation, Osteophytes translation, English dictionary definition of Osteophytes. n. See bone spur. os′te·o·phyt′ic adj. American Heritage® Dictionary of the English Language, Fifth Edition