et al. The effect of two different orthoses on pain, hand function, patient satisfaction and preference in patients with thumb carpometacarpal osteoarthritis: a multicentre, crossover, randomised controlled trial. Bone Joint J. 99-B, 237–244 (2017). PubMed Google Scholar Watt, F. E. et ...
Patient Identification Centres PIS: Participant Information Sheet PPIE: Patient and public involvement and engagement PSS: Personal social services QALYS: Quality-adjusted life years QAP: Qualitative analysis plan QoL: Quality of life SAE: Serious adverse event SAIL: Secure Anonymised Infor...
patient education should be addressed for all treatments 38OA awareness and perception in society requires improvement 39Emerging imaging and biomarker research will impact both on diagnosis and trial endpoints 41CHAPTER 3 R&D APPROACH 43Classification of marketed and pipeline OA drugs ...
Mutant mice are generated at the Sanger Institute as part of the International Mouse Phenotyping Consortium (IMPC). Mice undergo broad phenotyping using the International Mouse Phenotyping Resource of Standardized Screen (IMPReSS) that is completed at 16 weeks of age when tissues are harvested for fur...
Before the start of the study, the protocol, the case report form, the information sheet, and the patient consent form were submitted to the French advisory committee of research in health (CCTIRS). As the study was non-interventional and did not interfere with or modify the patient health...
Second, there was regular physiotherapy supervision and monitoring each week, including one-to-one supervised walking sessions or group supervised walking sessions based on patient preference, and regular phone calls or SMS reminders. Third, each participant wore a pedometer and recorded the number ...
Osteoarthritis causes debilitating pain and disability, resulting in a considerable socioeconomic burden, yet no drugs are available that prevent disease onset or progression. Here, we develop, validate and use rapid-throughput imaging techniques to iden
Further reasons for the positive evaluation of both interventions may be linked to the fact that perceived patient benefit is not only related to pain and functional outcomes, but also to factors relating to the instructor (personality, professionalism, motivational skills), program design (including ...
Background: Telerehabilitation to guide self-management has been shown to be a feasible care strategy for knee osteoarthritis (KOA). The aim of this study was to explore the effectiveness of a blended web-based rehabilitation program enhanced with outdoo
The randomised treatment of the next patient in the trial will be concealed to both administrative and OT staff until the point of randomisation. Randomisation will be completed using an allocation ratio of 1:1:1:1. Blinding/masking During the data collection phase, both the trial nurse and ...