subchondral bone structural changes, osteophytes formation, joint inflammation, and impaired function5. Chondrocytes, the sole cell type in articular cartilage, play a crucial role in maintaining the structure and function of cartilage6. In OA, there is an imbalance in the metabolism of the cartilag...
Intraobserver and interobserver (with a second reader) agreement of posteroanterior K&L score, skyline K&L score and lateral osteophytes were assessed on 100 knees. Unweighted kappas for intraobserver reliability were between 0.81 and 0.98; interobserver kappas were between 0.49 and 0.7627. The ...
Background: In normal knees, quadriceps contraction changes the shape of the prefemoral fat pad (PFP). However, in persons with knee osteoarthritis (OA), the functional or morphological changes of the PFP are unclear. This study aimed to clarify the morphological changes in the PFP in ...
Osteoarthritis (OA), a degenerative age-related disease that affects the joints, is the most common human musculoskeletal disorder and a leading cause of disability in elderly populations worldwide. The symptoms of OA include pain, morning stiffness, joint swelling, limited range of motion, decreased...
HSs were asked to fill in questionnaires related to pain intensity, anxiety, and depression.Results: Our results highlight that the levels of both free and total BDNF are significantly lower in pain patients compared to HSs, withpvalues of 0.041 and 0.024, respectively. The number of CD3−...
As determined by the OAI coordinating center at UC San Francisco, 4796 people aged 45 to 79 were enrolled by using the original dataset with KL grades for both knees. In addition, the data include bilateral posterior-anterior PA fixed flexion of knee X-ray images from the OAI. Figure 4 ...