A concern regarding long-term consequences of youth sports injury is the risk of developing osteoarthritis (OA) at a young age. Based on the available evidence, a link between youth sports injuries, particularly acute injury of the knee and ankle, and OA, is likely. Early OA development and...
Recent data suggest that the risk of paediatric sport injury is high and constitutes a significant public health burden. A concern regarding long-term consequences of youth sports injury is the risk of developing osteoarthritis (OA) at a young age. Based on the available evidence, a link between...
Irrespective of underlying mechanisms, the long-term efficacy of joint distraction in the treatment of severe ankle osteoarthritis at young age validates the concept of joint distraction in the treatment of osteoarthritis. Therefore, joint distraction in the case of severe ankle osteoarthritis may be a...
At the cellular and molecular level, OA is characterized by the alteration of the healthy homeostatic state toward a catabolic state. Aging One of the most common risk factors for OA is age. A majority of people over the age of 65 were diagnosed with radiographic changes in one or more ...
and 100 for hand OA.29The incidence of hand, hip, and knee OA increased with age, reached the peak level at 55–59 years old, and gradually declined in the older groups.13,29Women have a higher incidence of hand, foot, and knee OA, while men have a higher incidence of shoulder and...
The protection from cartilage degeneration in the female mice correlates with an increased expression of TGFβ1 and IL4 at 2 months of age. Conclusion: The increased expression of TGFβ1 and IL4 in young STR/ort female mice suggests that the sexual dimorphism is mediated through the articular...
Conclusions This study provides strong evidence that primary prevention of OA must be implemented in young adulthood to curtail the emergence of radiographically-defined OA at the mid-life. 展开 关键词: Osteoarthritis, Epidemiology, Prevalence, Race/Ethnicity ...
In several types of arthritis that resemble infectious joint disease, no causative agent has been isolated. Principal among these isrheumatoid arthritis. This disorder may appear at any age but is most usual in the fourth and fifth decades. A type that affects children is called juvenile rheumatoi...
Prevalence in men is slightly higher in the younger age groups (<45 years of age), whereas women are affected more commonly at ages older than 55 years, except for disease of the hip. The pattern of joint involvement in OA is strikingly affected by age, gender, previous joint injury, ...
Osteoarthritis is the most common cause of chronic disability in older adults. It is a slowly progressive degenerative disorder of articular joints that has multiple etiologies with age being a key factor. Osteoarthritis most commonly affects the hands,