The traditional biological principle for developing bone biomaterials is to directly stimulate the osteogenic differentiation of osteoblastic lineage cells, the direct effector cells for osteogenesis. This strategy has been successful for the
” another may see as unfit to be a human companion. Dogs straddle multiple levels of closeness to humans, filling “virtually every role in the whole spectrum of human-animal relationships” (Russell2011:280). It stands to reason, then, that...
Active 1,25(OH)₂D3can both positively and negatively regulate the expression of osteoblastic markers ofmineralizationdepending on the stage of osteoblast differentiation and adaptive responses tocalcium absorption[148]. In our studies, we identified five miRNAs that were differentially expressed upon ...
osteoporosis is frequently diagnosed after the first clinical fragility fracture. At this point, anti-osteoporosis therapy is overdue but is required to prevent further fragility fractures in these high-risk patients. Therefore, it is pivotal to assess the osteoporosis and individual fracture risk early...
Intraosseous Injection of rhBMP-2/Calcium Phosphate Matrix Improves Bone Structure and Strength in the Proximal Aspect of the Femur in Chronic Ovariectomiz... Background: Osteoporosis results in a decrease in bone density, bone quality, and strength throughout the skeleton. Despite systemic therapies...
Brickman AS, Massry SG, Coburn JW: changes in serum and urinary calcium during treatment with hydrochlorothiazide: studies on mechanisms. The Journal of clinical investigation. 1972, 51 (4): 945-954. Article CAS PubMed PubMed Central Google Scholar Gamba G: Molecular physiology and pathophysiolog...
We used calcium phosphate deposition as an indicator of cell differentiation in scaffolds using von Kossa staining (Figure 13). Recently, different approaches have been performed to obtain bone fillers. A protein extract of bone extracellular matrix with polycaprolactone, [18] hydroxyapatite granules obt...
[18] reported that lower intake of calcium was significantly associated with both osteosarcopenia and OSA, while physical activity was the lowest among the participants with OSA. In Choi et al.’s study [19], protein intake below the Korean recommendation (~0.9 g/kg body weight) was ...
Uric acid crystals cause arthritis in gout, while calcium pyrophosphate crystals cause arthritis in pseudogout. Some people are born with abnormally formed joints (congenital abnormalities) that are vulnerable to mechanical wear, causing early degeneration and loss of joint cartilage. Osteoarthritis of ...
Effectiveness of intra-articular injections of sodium bicarbonate and calcium gluconate in the treatment of osteoarthritis of the knee:a randomized double-blind clinical trial. García-Padilla S,Duarte-Vázquez MA,Gonzalez-Romero KE,et al. BMC Musculoskeletal Disorders . 2015...