IL-22 has been shown to activate STAT1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. The functional IL-22 receptor complex consists of two receptor subunits, IL-22...
Formulation Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4. Biological activity Fully biologically active when compared to standard substance. Measured by its ability to induce IFN-gamma secretion by KG1 human acute myelogenous leukemia cells. The ED50 for this effect is 1.5-15ng...
Lyophilized from a 0.2mm filtered solutionin20mM PB,150mM NaCl, pH7.4, with 0.02% Tween 20. Biological activity Fully biologically active when compared to standard. The ED50as determined by the M1 cell differentiation assay is ≤ 0.05ng/ml, corresponding to a specific activity of ≥ 2 x107...