Bioorthogonal ligationortho-quinone methidevinyl thioetherchemical genetic hetero-Diels-Alder cycloadditionprotein labelingBioorthogonal ligations have found widespread use in biomedical research for site selective labeling of biomolecules in living systems. Discovering new reactions to expand the toolbox of ...
ortho-quinone methide (o-QMs)modified Mannich reactioncycloadditionNMR spectroscopyconformational analysisDFT calculationsTo synthesize functionalized Mannich bases that can serve two different types of ortho‐quinone methide (o‐QM) intermediates, 2‐naphthol and 6‐hydroxyquinoline were reacted with ...
Trapping labile adducts formed between an ortho-quinone methide and DNA. Exogenously generated electrophiles are capable of alkylating DNA. If not repaired, the resulting DNA adducts can lead to mutations and either cancer or c... MP Mccrane - University of Maryland, College Park. 被引量: 0...
situ generation of ortho‐quinone methides (o‐QMs) and their subsequent cycloaddition reaction with unactivated alkenes provided chromanes with excellent diastereo‐ and enantioselectivity.关键词: chromanes cycloaddition homogeneous catalysis n‐triflylphosphoramide ortho‐quinone methide ...
Biomimetic eplone via ortho-quinonemethide methide oxidopyrilium cycloadd to tropoloneBaldwin, J E
The reaction proceeds through in situ vinylidene ortho‐quinone methide (VQM) intermediate formation. The styrene derivatives were obtained in good to high ... C Parida,M Devi,S Chandra Pan - 《European Journal of Organic Chemistry》 被引量: 0发表: 2024年 Asymmetric synthesis of chromene skelet...
Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol to gamma-Butyrolacto... Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol ...
0 (Indolequinones) 138230-21-4 (quinone methide) 70FD1KFU70 (Sulfur) 7440-44-0 (Carbon) PreMedline Identifier: 36121104From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.Printer-Friendly Download Thisprocessing...Find...
Stereoselective Synthesis of Atropisomeric Acridinium Salts by the Catalyst-Controlled Cyclization of ortho-Quinone Methide Iminiums Quinone methides are fundamental intermediates for a wide range of reactions in which catalyst stereocontrol is often achieved by hydrogen bonding. Herein,... X Wu,C Sparr...
ortho-quinone methide species, which was generated in situ at low temperature by the sequential addition of methylmagnesium bromide and di-tert-butyl ... JC Green,S Jiménez-Alonso,ER Brown,... - 《Organic Letters》 被引量: 50发表: 2011年 ...