药物临床试验是指研究药物的有效性、安全性和质量等问题,以考察其能否上市用于特定人群的临床试验。全球临床试验数据库收录了美国临床试验数据库、EUCTR等18个注册机构及两百多个国家的临床试验研究信息,覆盖药物、生物制品、医疗设备的临床试验数据,数据丰富,功能强大。展开...
ORION-10是一项评估inclisran治疗ASCVD和LDL-C升高患者的疗效和安全性的3期试验。 Methods:ORION-10 is a Phase 3, placebo-controlled, double-blind, randomized study in 1561 subjects ≥18 years of age with stable ASCVD and elevated LDL-C (≥70 mg/dL) despite maximum tolerated oral statin therapie...
Efficacy and safety of inclisiran in patients with established cerebrovascular disease: pooled, post hoc analysis of the ORION-9, ORION-10 and ORION-11, phase 3 randomised clinical trialsPharmacotherapyBACKGROUND. Patients (pts) with hyperlipidaemia and established cerebrovascular disease (CeVD) are ...
研究的主要有效性终点为从仅inclisiran治疗组患者从ORION-1研究开始至开放标签拓展研究阶段的第210天内LDL-C水平的变化百分比(意向治疗分析人群的inclisiran暴露时间约为570天)。次要和探索性终点还包括随访1440(4年)内的LDL-C和PCSK9...
material impact on the projected cost structure within a single year. Orion often undertakes the last, in other words Phase III, clinical trials in collaboration with other pharmaceutical companies. Commencement of these collaboration relationships and their structure also materially affect the schedule ...
Clinical Trials Determine Orion Corp go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy. 160+ Marketed Drugs Understand Orion Corp’s commercialized product portfolio to stay one step ahead of the market. 50+ Catalyst Calendar Proact...
4. https://clinicaltrials.gov/ct2/show/NCT03060577?term=NCT03060577 5. https://eppro02.ativ.me/src/EventPilot/php/express/web/planner.php?id=AHA22 6. The Nobel Prize in Physiology or Medicine 2006. https://www...
Nikkola Jussi Mikael, Lääketieteen tohtori, Tampereen yliopisto, Randomized Clinical Trials Evaluating Urine DNA Testing as a Substitute for Cystoscopy in Urothelial Carcinoma Diagnostics and Surveillance, 40,000 € Puris Elena, Provisor, Itä-Suomen yliopisto Kuopion kampus, A.I. Virt...
and digital front door. Orion Health's products facilitate data integration across healthcare systems, improve clinical safety and efficiency, and support patients in their healthcare journey. It was founded in 1993 and is based in Auckland, New Zealand. In December 2024, Orion Health was acquired...
SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med. 2013;158:200–7. https://doi.org/10.7326/0003-4819-158-3-201302050-00583. Article PubMed PubMed Central Google Scholar Kawakami N, Tsutsumi A. The stress check program: a new national policy for ...