the composition of the regenerative niche has remained largely elusive. Here, we dissected the diversity of activated cell states in the regenerating zebrafish heart based on single-cell transcriptomics and spatiotemporal analysis. We observed the emergence of several transient cell states with fibroblast...
Compared to small PAVs, large-size PAVs bring instability of the genome, possibly resulting in their failure in the transmission to the subsequent generations [20]. Coding genes and/or regulatory elements within large PAVs may lead to deleterious or even lethal lesions for biological function or...
Yak has been subject to natural selection, human domestication and interspecific introgression during its evolution. However, genetic variants favored by each of these processes have not been distinguished previously. We constructed a graph-genome for 47 genomes of 7 cross-fertile bovine species. This ...
Microalbuminuria and diabetic renal disease are closely linked [1–14] and are associated with increasing blood pressure and often antecedent hyperfiltration [1]. Microalbuminuria usually indicates the beginning of diabetic nephropathy as opposed to over
The annotated genes were embedded within a sea of transposable element (TE) relicts and other repetitive sequences, which accounted for 65.94% of the patchouli genome (Supplementary Table6, Fig.1). We detected full-length TEs with solid structures and estimated their insertion times (Supplementary...