Orientia tsutsugamushi (OT), the causative agent of the vector-borne Scrub typhus zoonotic disease in humans, is a unique microorganism that exists in the Asia-Pacific region since a long time. In spite of its
Tsutsugamushi Disease Tsutsugamushi disease is a mite-borne rickettsiosis of humans that is endemic in eastern and southern Asia, the western Pacific region, along the northern coast of Australia (Queensland and Northern Territory), and the Indian subcontinent. Cases may occur as far west as Afghan...
but it was first documented in the medical literature as tsutsugamushi disease in 1879 (Nagayo et al.1917). The name was derived from the Japanese “tsutsuga” meaning illness and “mushi” meaning insect, in reference to the source of infection,...
We detected Orientia tsutsugamushi from samples collected in May (2nd week) using INNOPLEX TSUTSU detection kit. There has been no sign of an epidemic disease caused by climate change with the exception of tsutsugamushi infection in Korea until now. But, it is gradually requiring continuous ...
(n = 8 per group) were intravenously injected in the tail vein with 1.25 × 106genome copies ofO. tsutsugamushiof either Karp strain or UT176 strain. TheO. tsutsugamushiinoculum was derived fromO. tsutsugamushi-infected L929 cells (kind gift from Stuart Blacksell, Mahidol Oxford ...
tsutsugamushi. Scrub typhus has been endemic to southern China for decades, and it occurs mainly in summer and winter. The disease had not been reported in northern China until the first outbreak in Linyi City, Shandong Province in 1986[7], and it occurs mainly in autumn and winter[8]; ...
Scrub typhus is a vector-borne infectious disease caused by Orientia tsutsugamushi and it is reportedly associated with up to 20 % of hospitalized cases of febrile illnesses. The major challenge of vaccine development is the lack of identified antigens that can induce both heterotypic and homotypic...
Scrub typhus of tsutsugamushi disease is an acute, febrile disease caused by infection with Orientia tsutsugamushi. O. tsutsugamushi is a gram-negative bacterium but has neither lipopolysaccharide nor a peptidoglycan layer. Orientia isolates are highly variable in their antigenic properties. The major ...
Orientia tsutsugamushi (Ott) is a causative agent of chigger‐borne zoonosis, scrub typhus which is life threatening and highly pervasive illness in humans. In this report, we have mined and classified the proteins involved in pathways unique to Ott by using high‐throughput computational ...
A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi for the Karp, Kato and Gilli