It is therefore perhaps not surprising that, as reviewed in this chapter, the organization, structure and mechanisms of expression of genes in methanogens appear superficially very similar to their bacterial counterparts. Cloning and sequencing has, however, revealed that many methanogen genes are more...
Primary structure of tetranectin, a plasminogen kringle 4 binding plasma protein: homology with asialoglycoprotein receptors and cartilage proteoglycan cor... A human genomic DNA library was screened by using conditions of reduced stringency with a bovine cDNA probe coding for the kringle domains in...
CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome Genome function depends on its 3D organization. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct territories with respect to each... L Baranello,F Kouzine,D Levens - 《Proceedings of the Nat...
Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II 来自 NCBI 喜欢 0 阅读量: 30 作者:J Ricky,N Christoforos,R Joaquim 摘要: Cellular DNA topoisomerases (topo I and topo II) are highly conserved enzymes that regulate the topology of DNA during normal genome ...
The mitochondrial genome encodes core subunits of the respiratory chain that drives oxidative phosphorylation and is, therefore, essential for energy conversion. Advances in high-throughput sequencing technologies and cryoelectron microscopy have shed light on the structure and organization of the mitochondria...
Southern blot hybridization of genomic DNA fragments revealed three divergent classes of PAL genes in the bean genome. Polymorphic forms were observed within each class. The nucleotide sequences of two PAL genes, gPAL2 (class II) and gPAL3 (class III), were determined. gPAL2 contains an open...
The nucleolus is the largest compartment of the cell nucleus and is where ribosomal RNAs (rRNAs) are synthesized, processed and assembled with ribosomal proteins. In addition to rRNA gene clusters that build the core of this subnuclear structure, nucleoli are associated with condensed chromatin. Al...
Although a number of experiments have shown that mechanical cues can also modulate gene expression, the underlying mechanisms are far from clear. Nevertheless, we are now beginning to understand how mechanical cues are transduced to the nucleus and how they influence nuclear mechanics, genome ...
The distribution of nucleosomes along the genome is a significant aspect of chromatin structure and is thought to influence gene regulation through modulat... PV Kharchenko,CJ Woo,MY Tolstorukov,... - 《Genome Research》 被引量: 68发表: 2008年 加载更多来源...
The integrin alpha8 is highly expressed during kidney and lung development. alpha8-deficient mice display abnormal renal development suggesting that alpha8 plays a critical role in organogenesis. Therefore, it would be of considerable interest to understand the genomic structure, localization and sequence...