Organic compounds and their uses本发明涉及用于诊断和治疗与Hedgehog通路有关的病变,包括但不限于肿瘤形成,癌症,瘤形成和非恶性过度增殖性疾病的化合物;特别是涉及式I化合物. The present invention relates to the diagnosis and treatment of diseases related to the Hedgehog pathway, including but not limited ...
1.1 Volatile organic compounds and their importance as flavoring agents Volatile organic compounds (VOCs) are described as carbon-based solids and liquids capable of entering the gas phase by vaporization at 0.01 kPa and temperatures near 20 °C (Pagans, Font, & Sánchez, 2006). These compounds ...
X-ray diffraction and X-ray photoelectron spectroscopy have been used to identify the structure of organic compounds, and are widely used in various fields such as organic chemistry, materials chemistry, pharmacology, and clinical medicine. The various complementary structural information obtained from th...
Metal organic compounds are used more effectively, with their material utilization ranging from 20 to 50%. In scaling up to 10 MW/year production using MOCVD, the current designs of flat-plate III–V modules require several tons of arsine and hydrogen. These quantities can be effectively ...
Polymerizations in living systems can effectively regulate cell functions and behaviors, but their uses have been hindered by the existence of complicated intracorporal interferences, the needs of high concentration of monomers and extra stimulates. Here, the authors address these issues by developing a...
Organic chemistry is the study of the synthesis, structure, reactivity and properties of the diverse group of chemical compounds primarily constructed of carbon. All life on earth is carbon-based, thus organic chemistry is also the basis of biochemistry. The ability to form compounds containing long...
amine, any member of a family of nitrogen-containingorganic compoundsthat is derived, either in principle or in practice, fromammonia(NH3). Naturally occurring amines include thealkaloids, which are present in certain plants; the catecholamineneurotransmitters(i.e.,dopamine,epinephrine, and norepinephrin...
HuR and to organic compounds of formula I wherein R1, R2 and R3 are as defined above and their use, e.g. as an inhibitor on the complex-formation of an ARE-containing mRNA and a target protein.Application Number: 11/815235 Publication Date: 01/01/2009 ...
The present invention provides organoselenium compounds comprising dibenzoselenophene, benzo[b]selenophene or benzo[c]selenophene and their uses in organic light emitting devices.</
Screening for compounds which inhibit the tyrosine kinase activity of the polypeptides of the invention may be done for example by using an isolated polypeptide of the invention in any in vitro tyrosine kinase phosphorylation assay known in the art and determining the potential of a compound to inh...