Raman spectroscopy relies on inelastic scattering of incident monochromatic light, wherein the energy of photons is being changed, either by a Stokes or anti-Stokes process, upon interaction with molecules of the sample. Light scattering on different types of biomolecules generates corresponding bands ...
The core enzyme phosphotransacylase (PTAC) recycles Coenzyme A and generates an acyl phosphate that can serve as an energy source. The PTAC predominantly associated with metabolosomes (PduL) has no sequence homology to the PTAC ubiquitous among fermentative bacteria (Pta). Here, we report two...
filaments indicating that both proteins nucleate rather than elongate actin filaments (Fig.3e). Finally, we examined the disassembly of preformed actin filaments in the presence of Mm-SPIRE1-KW and Mm-SPIRE1-KW-ΔB,C. Increasing the concentration of Mm-SPIRE1-KW from 20 – 500 nM promoted...
Perturbation: a transition from the normal state (state 1) to a chronic malfunctioning of one subsystem (a) during generates internal damage (orange thread) that requires a higher load of the shared PQC factor (red circles) to assuage. As a consequence, the PQC factor becomes limited at ...
Non-shivering thermogenesis relies primarily on mitochondrial uncoupling protein 1 (UCP1) in thermogenic fat (including brown and beige adipose tissue) to burn substrates, such as fatty acids (FAs), and convert chemical energy into heat. Lipid droplets (LDs), which are organelles that store ...
Campanella JJ, Bitincka L, Smalley J: MatGAT: an application that generates similarity/identity matrices using protein or DNA sequences. BMCBioinformatics. 2003, 4: 29-10.1186/1471-2105-4-29. Google Scholar Plewczynski D, Slabinski L, Tkacz A, Kajan L, Holm L, Ginalski K, Rychlewski...
Campanella JJ, Bitincka L, Smalley J: MatGAT: an application that generates similarity/identity matrices using protein or DNA sequences. BMCBioinformatics. 2003, 4: 29-10.1186/1471-2105-4-29. Google Scholar Plewczynski D, Slabinski L, Tkacz A, Kajan L, Holm L, Ginalski K, Rychlewski...
Migration of meiosis-I (MI) spindle from the cell center to a sub-cortical location is a critical step for mouse oocytes to undergo asymmetric meiotic cell division. In this study, we investigate the mechanism by which formin-2 (FMN2) orchestrates the in
A product of transcription that generates RNA molecules that encode more than one protein. MELAS (Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes). A mitochondrial disease that is most commonly caused by a mutation (m.3243A>G) in the mitochondrial DNA-encoded tRNALeu(UUR...
This purification step generates contaminants and loss of key components, and has to be designed considering that isolated MCS have features of both organelles. Other approaches, such as proximity labelling techniques, have overcome the requirement of isolating the compartment of interest. Methods based...