Describe the functions of the Golgi complex within the cell cytoplasm. What do you consider the most important structure or organelle in a living cell, and why? List the membranous organelles of a eukaryotic cell, and describe the function of each. ...
2b, Supplementary Data 1) and, instead of hand-picking a few candidates, we visualized this list as a protein–protein interaction network to identify the most biologically interconnected clusters of proteins, which could infer TMEM16K function (Fig. 2b). First, we calculated protein–protein ...
At the end of an organelle proteomic investigation, investigators are left with a long list of proteins whose location needs to be verified by an orthogonal method, a daunting prospect; or, they must accept an unknown and possibly very high level of incorrect localizations. Some of these ...
Loss of spliceosomal machinery impairs the mRNA splicing, leading to accumulation of unprocessed RNAs in the parasite and thus dysregulate vital cellular functions, which in turn leads to execution of apoptosis-like cell death. Our results establish one of the possible mechanisms of instigation of ...
(genomic context and co-expression data) to create the interaction network of the targeted proteins, we used Cytoscape version 2.8.1. List of Uniprot identifiers of each target protein were provided as input to the PISCQUISC web client plugin to build the network. Wherever there were multiple ...
coli 30 S subunit proteins exist in plastid 30 S subunit (Table I), the origins and functions of the four additional proteins are intriguing. PSRP-1 has 58.3% sequence similarity with the hypothetical translation product of a light-repressed transcript (lrtA) gene ofSynechococcus PCC 7002 (44...
At the end of an organelle proteomic investigation, investigators are left with a long list of proteins whose location needs to be verified by an orthogonal method, a daunting prospect; or, they must accept an unknown and possibly very high level of incorrect localizations. Some of these ...
Cilia or flagella have been around since almost the beginning of life, and have now developed specialized cell-type specific functions from locomotion to acting as environmental sensors participating in cell signalling. Genetic defects affecting cilia result in a myriad of pathological instances, ...
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Strains and culture conditions Table 1 List of strains. Full size table Table 2 List of plasmids. Full size table Plasmid construction pRS416-PVph1-Vph1 carries aVPH1gene under the control of the endogenous promoter (the region 500 bp upstream of the ORF). TheVPH1gene in the vector contain...