Transcriptomic analyses have contributed with valuable information regarding the physiology of several parasites, including ticks7,8. The genomes ofIxodes persulcatus,Ixodes scapularis,Haemaphysalis longicornis,Dermacentor silvarum,Hyalomma asiaticum,Rhipicephalus sanguineus, andRhipicephalus microplushave been sequen...
There were frequently deep-seated cultural attitudes which influenced views and perceptions of deceased organ donation, often related to associations with trafficking and selling organs and dismembering of bodies. These lay perceptions and views (particularly from people from ethnic minority group) were ...
The liver’s anatomical location, which may serve as a trafficking hub for CRC cells to spread to other organs, possibly underlies this finding53. By modeling large autopsy data sets in mCRC, Newton et al. highlighted that liver metastases could serve as tumor spreaders54, and that there ...
2023, Plant Cell Reports Lipid-mediated activation of plasma membrane-localized deubiquitylating enzymes modulate endosomal trafficking 2022, Nature Communications Developing Genetic Engineering Techniques for Control of Seed Size and Yield 2022, International Journal of Molecular Sciences The diverse roles of...
Innate DNA sensing via the cyclic GMP-AMP synthase–stimulator of interferon genes (cGAS–STING) mechanism surveys microbial invasion and cellular damage and thus participates in various human infectious diseases, autoimmune diseases and cancers. However, how DNA sensing rapidly and adaptively shapes cell...
The ability of EVs to protect a wide variety of nucleic acid species [2], carry these across biological barriers [50,51,52], utilise endogenous intracellular trafficking mechanisms and trigger a response in recipient cells [53] makes them attractive drug delivery systems for both endogenous and ...
Microfluidic devices have been used recently to gain new insights into the trafficking and accumulation of pathological Aβ and Tau in human cells [108]. Table 3. Various brain-on-a-chip materials, sensors, and cell types. 4.8. Nerve-on-a-Chip Experimental models of neurodegenerative ...