python genomics genetics open biology reading dna protein frame sequence molecular nucleotides orf targets codon Updated Dec 21, 2020 Python averissimo / webapp_orf_finder Star 0 Code Issues Pull requests rails bioinformatics rna-seq orf Updated Feb 16, 2019 Ruby peter...
To generate read coverage plots across the ORF, reads were first aligned to the human ORFeome using Bowtie253(version 2.2.3) using “—local” option with default parameters. The alignment file, in SAM format, was parsed using SAMtools54(version 1.2) and custom Python scripts were used to ...
The pathology and genetics of ALS overlap with another neurodegenerative disease, frontotemporal dementia (FTD), which is the second most common cause of dementia in patients under 65 years4. Aggregates of the RNA-binding transactive response DNA binding 43 protein (TDP-43) accumulate in neurons...