Nanotechnology Enhancing oral gene delivery through carrier selectionplasmid design and macroformulation THE JOHNS HOPKINS UNIVERSITY Hai-Quan Mao LooYihuaGene therapy is a promising treatment option for various inherited and acquired diseases. Non-viral oral gene delivery is especially attractive due to ...
Schnurch, Oral gene delivery: design of polymeric carrier systems shielding toward intestinal enzymatic attack, Biopolymers 83 (2006) 327-336.R. Martien, B. Loretz, A. Bernkop-Schnűrch, Oral gene delivery: design of polymeric carrier systems shielding toward intestinal enzymatic attack, ...
The affinity of L. lactis to eosinophils can function as a novel targeting strategy for oral DNA delivery [235]. The facultative anaerobic characteristic of E. coli was also exploited for hypoxia-targeted gene delivery. Show abstract1 Current address: Denka Seiken Co. Ltd., Niigata 959-1695, ...
Eosinophils are the main cellular targets for oral gene delivery using Lactic acid bacteria 来自 国家科技图书文献中心 喜欢 0 阅读量: 37 作者:K Takahashi,N Orito,D Yanagisawa,A Yano,N Inoue 摘要: Lactic acid bacteria have been studied as a vehicle for the delivery of plasmid DNA to the ...
Oral Session: Cytokines/Gene TherapyCYTOKINESGENE therapyBone Marrow Transplantation (2003) 31, S16-S19. doi:10.1038/sj.bmt.1703966doi:10.1038/sj.bmt.1703966NoneBone Marrow Transplantation
Gene therapy-its potential in the management of oral cancerShillitoeE.J.LapeyreJ.-N.Adler-StorthzK.ingentaconnectEuropean Journal of Cancer B Oral OncologyORAL ONCOLOGY, EUROPEAN JOURNAL OF CANCER, Volume 30B, Number 03, issued 1994, SHILLITOE et al., " Gene Therapy - Its Potential in the ...
Oral squamous cell carcinoma (OSCC) is the most common phenotype of oral cancer. N-myc downstream regulated gene 1 (NDRG1) is a modulator for cell proliferation, differentiation, and invasion. The role and function of NDRG1 in OSCC cells remain inconclusive. The 3H-thymidine incorporation and...
This study was designed to examine associations of five VEGF-Cgene polymorphisms with the susceptibility to and clinicopathological characteristics of oral squamous cell carcinoma.Otolaryngology: Head and Neck SurgeryMu-Kuan Chen, MD presenter
With the advances in immunotherapy and the challenge of poor responsiveness in oral squamous cell carcinoma (OSCC) patients, understanding the tumor microenvironment is crucial. Radiogenomics offers the potential to provide pre-operative, non-invasive image-derived immune biomarkers. To this aim, the ...
1) oral gene therapy 口服基因治疗 1. A novel shuttle plasmid which can be replicated in yeast and expressed in mammal cell is required inoral gene therapywith yeast as vector to deliver target gene. 为研究酵母作为载体在口服基因治疗及免疫中的作用 ,需要一种能够在酵母中复制而在哺乳动物细胞中表...