Although a myriad of papers have been published regarding intravenous to oral (IV to PO) therapy conversion programs and about clinical pharmacy services provided in hospitals, little is known on the role of hospital pharmacists in promoting the oral route for potassium administration. Objective The ...
ConversionInterventionsIntravenous administrationOral administrationPharmacistPotassium chlorideBackground Guidelines recommend use of the oral route whenever possible to treat or prevent hypokalemia. Although a myriad of papers have been published regarding intravenous to oral (IV to PO) therapy conversion ...
Monitor blood pressure and potassium levels and manage as necessary. Management of pseudoaldosteronism may include discontinuation of itraconazole, substitution with an appropriate antifungal drug that is not associated with pseudoaldosteronism, or use of aldosterone receptor antagonists. Interaction Potential...
In oral drug delivery, the most commonly used counterions over the past three decades include hydrochloride, maleate, mesylate, and phosphate for basic drugs, and calcium, magnesium, potassium, and sodium for acidic drugs [77]. Selection of appropriate base, salt or a polymorphic form with ...
7.3 Agents Increasing Serum Potassium Enalapril attenuates potassium loss caused by thiazide-type diuretics. Potassium-sparing diuretics (e.g., spironolactone, triamterene, or amiloride), potassium supplements, or potassium-containing salt substitutes may lead to significant increases in serum potassium. 7.4...
had an antioxidant effect, reducing 50% of fast blood glucose (p< 0.05) and 25% of the TyG index, which is used to estimate insulin resistance (p< 0.05), compared with the non-treated group. The oxidovanadium–sulfur compound is a promising antihyperglycemic therapeutic, including in cases ...
(1:1 dose conversion). The Gengraf®dose should subsequently be adjusted to attain the pre-conversion cyclosporine blood trough concentration. Using the same trough concentration target range for Gengraf®as for Sandimmune®(cyclosporine) results in greater cyclosporine exposure when Gengraf®is...
(hypokalemia, low serum renin and aldosterone, and elevated 11-deoxycortisol), has been reported with itraconazole use in the postmarketing setting. Monitor blood pressure and potassium levels and manage as necessary. Management of pseudoaldosteronism may include discontinuation of Itraconazole Oral ...
In this study aliskiren was well-tolerated in all treatment groups, consistent with previous findings that aliskiren has a safety profile equivalent to the ARBs losartan and irbesartan, and placebo (32, 33). Clinically significant elevations in potassium levels were reported in two patients receiving...
Conversion from Gengraf® to Sandimmune® should be made with increased monitoring to avoid the potential of underdosing. Kidney, Liver, and Heart Transplant Nephrotoxicity Cyclosporine, the active ingredient of Gengraf® Oral Solution (cyclosporine oral solution, USP [MODIFIED]), can cause ...