Oral mucositis (OM) is one of the most impacting oral complications negatively affecting the quality of life of cancer patients being treated with high-dose chemotherapy and radiation of the head and neck. It is an acute adverse effect that can be devastating and could affect cancer prognosis. ...
Complications of cancer therapy depend on the type of malignancy and location, the treatment modality used (ie, agents, sequencing, rate of delivery, dosage), and host factors. For example, the severity of oral mucositis following radiation therapy depends on the ionizing radiation used, the rate...
Mucositis affects all gastro-intestinal tract and oral cavity inducing patient pain, inability to eat, weight loss and local infection. Furthermore, patients affected by a high-grade mucositis have to reduce chemotherapy regimen with delayed cancer treatment and worse prognosis. About 30–40% of can...
In patients receiving treatment for cancer, does oral cryotherapy prevent oral mucositis? Oral cryotherapy is effective for the prevention of oral mucositis in adults receiving fluorouracil-based chemotherapy for solid cancers, and for the prevention of severe oral mucositis in adults receiving high-dose...
Worthington HV, Clarkson JE, Bryan G, Furness S, Glenny AM, Littlewood A, McCabe MG, Meyer S, Khalid T (2010) Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev (12):CD000978 ...
Interventions for preventing oral mucositis for patients with cancer receiving treatment 2007, Cochrane Database of Systematic Reviews Oral mucositis 2006, Oral Diseases Benzydamine HCl for prophylaxis of radiation-induced oral mucositis: Results from a multicenter, randomized, double-blind, placebo-controlle...
oral mucositis within two to three weeks of radiation therapy, increasing to the end of care and resolving one to two, or more months following treatment over. In SCT patients, symptoms arise one to two weeks after chemotherapy, and may persist for weeks. The impact is significant due to ...
Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy Oral mucositis is a side effect of chemotherapy, head and neck radiotherapy, and targeted therapy, affecting over 75% of high risk patients. Ulceration can... P Riley,AM Glenny,HV Worthington,...
Oral mucositis (OM), also referred to as stomatitis, can negatively impact radiation and chemotherapy treatment schedules and add to oncology patients’ emotional and physical distress. About 35% to 40% of patients treated with cytotoxic chemotherapy wil
Clarkson J E, Worthington H V, Furness S, McCabe M, Khalid T, Meyer S . Interventions for treating oral mucositis for patients with cancer receiving treatment.Cochrane Database Syst Rev2010; CD001973. doi: 10.1002/14651858.CD001973.pub4. ...