hair disordersminoxidiloral minoxidiltopical minoxidilMinoxidil is a strong arterial vasodilator, first introduced as an antihypertensive medication. In dermatology, topical minoxidil (TMX) has been used for many types of alopecia. TMX is not FDA-approved in patients under 18 years old and there are ...
hair lossminoxidiloral minoxidilsafetysystemic minoxidilBackground Although topical minoxidil is an effective treatment option for hair loss, many patients are poorly compliant due to the necessity to apply the medication twice a day, undesirable hair texture, and scalp irritation. Objective In recent ...
In this week’s Pointers with Dr Portela, the 208SkinDoc discusses what patients need to know about oral minoxidil for hair loss. Dustin Portela, DO, a board-certified dermatologist and dermatologic surgeon at Treasure Valley Dermatology in Boise, Idaho, talks about what patients should know ...
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Topical minoxidil (TM) is the only FDA-approved medication for the treatment of female pattern hair loss (FPHL).1 Minoxidil is a pro-drug. TM efficacy in FPHL requires bio-activation into minoxidil sulfate by sulfotransferase enzymes.2 Sulfotransferases are xenobiotic metabolizing enzymes expressed...
Interventions Participants were randomized 1:1 into 2 groups: oral minoxidil, 5 mg, daily and topical placebo solution; or 1 mL of topical minoxidil, 5%, twice daily and oral placebo for 24 weeks. Main Outcomes and Measures The primary outcome was change in terminal hair density...
Combination tofacitinib and oral minoxidil therapy in alopecia areata may be superior to tofacitinib alone, according to findings published in theJournal of the American Academy of Dermatology. “Janus kinase inhibitors are emerging as an important therapy...
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The efficacy of low-dose oral minoxidil for the treatment of alopecia may not be affected by the concomitant use of mechanistically antagonistic medications, according to a retrospective study. Changes in median trichometric width and density were 5.5 μm and 18.5 hairs/cm2 for those concurrently ...
Late alopecia, defined as incomplete hair regrowth>6months following cytotoxic chemotherapy or>6months from initiation of endocrine therapy, negatively impacts quality of life and may affect dose intensity of adjuvant therapy. This study investigates the effect of oral minoxidil in women with chemotherapy...