Release of antibiotics into the colon, for example, may disrupt the delicate balance of the natural flora and result in conditions such as pseudomembranous colitis. Most oral dosage forms, especially controlled release dosage forms, have the potential to deliver a significant amount of drug to the ...
On the other hand, the difference in the Sp and Rv physical mixture gel arrangements, which happened spontaneously depending on the hydrophilic/lipophilic balance, might have interfered with the Sp hydrophobic amino acids with the Rv inside the NA hydrogel in contact with the intestinal–colonic ...