itraconazole inhibits the14C-demethylation step in the synthesis of ergosterol, a cell wall component of fungi. Ergosterol is the active site for amphotericin B. In one study the antifungal activity of amphotericin B againstAspergillus fumigatusinfections in mice was inhibited by ketoconazole therapy. ...
Pharmacoeconomic analyses are becoming an increasingly integral component of the overall profile of new drugs. This is particularly true for terbinafine an... JL Bootman - 《Journal of the American Academy of Dermatology》 被引量: 47发表: 1998年 Successful treatment of toenail mycosis with terbinaf...