Absorption of oral antibiotics was assessed by determining the trough serum bactericidal titers for the infecting organism; whenever feasible, the dosages were adjusted to achieve trough titers greater than or equal to 1:8. The follow-up period ranged from six to 66 months (mean, 42.4 months)....
Oral antibiotics confer small benefits and small harms in low-risk children with acute otitis mediaHumansOtitis MediaAnti-Bacterial AgentsThe article focuses on the effectiveness of antibiotics for acute otitis media (AOM), middle ear infection, in children. Topics include the randomized controlled ...
AMPs are expected in the future to be used as models for designing effective oral microbial antibiotics.References Abiko et al., 2002 Y. Abiko, Y. Jinbu, T. Noguchi, M. Nishimura, K. Kusano, P. Amaratunga, T. Shibata, T. Kaku Upregulation of human beta-defensin 2 peptide expression ...
The ISO10932: 2010 minimal inhibitory concentration (MIC) values for the 20 antibiotics tested on L. gasseri HHuMIN D were used. 1. For this experiment, LSM-Cys (LAB susceptibility test) medium containing 0.03% (w/v) L-cysteine HCl was used with 96-well plates. Upon diluting ...
Periodontitis is the most widespread oral disease and is closely related to the oral microbiota. The oral microbiota is adversely affected by some pharmacologic treatments. Systemic antibiotics are widely used for infectious diseases but can lead to gut
The Committee on Safety of Medicines reviewed the UK experience with desensitization in 1986, weighing efficacy against risk. They considered the evidence for efficacy and found it convincing forragweed pollen, bee and wasp venom, and some antibiotics, but thought the evidence for grass pollen and ...
The significance of mutagenicity findings relative to the therapeutic use of nitrofurantoin in humans is unknown. Impairment of Fertility The administration of high doses of nitrofurantoin to rats causes temporary spermatogenic arrest; this is reversible on discontinuing the drug. 16. How is Nitrofurant...
A statistically significant (p-value < 0.01, statistic 1686390, alpha 0.05, effect size 0.87) difference was found between the mean ASI for IV and oral antibiotics upon switching (8.25 and 5.89 respectively) through the Wilcoxon rank-sum test. In addition, the majority of patients (70.03%...
HIOEC were grown in Keratinocyte Serum Free Medium containing bovine pituitary extract (Cat No. 10744019, Lot No. 2120576; Thermo Fisher Scientific, USA) with antibiotics (100 U·mL−1penicillin and 100 U·mL−1streptomycin; Hyclone, USA). When cells reached ~90% confluency, the mediu...
against dental carie–causing organisms, includingStreptococcus mutans.127These results suggest that plant-derived compounds with proven efficacy against pathogenicoral microorganismscould be incorporated into dental health programs to reduce the usage of antibiotics, as combination therapies, and to improve ...