Administration of Preoperative Oral Antibiotics is a Risk Factor for Postoperative MRSA EnterocolitisTuberculosisDrug susceptibility testingMultidrug resistance tuberculosisREMAThe antimicrobial era is threatened by high levels of antibiotic resistance, the limited number and disparate availability of effective ...
Remarkably, in the past 30 years no new antibiotic class effective against MRSA has been discovered [8] and received regulatory approval. This necessitates the medicinal chemistry community to respond to the need for developing new antibiotics with novel chemical scaffolds. The phenylthiazoles develope...
however, both of these methods necessitate considerable effort and manual skill [35]. The adjunctive use of regional antibiotics may present an alternative therapeutic approach for oral infectious diseases. However, bacterial biofilm is difficult to eradicate in vivo with minimal antibiotic concentrations ...
Antibiotic stewardship is of great importance in such a dismal situation but stringent adherence to infection control measures is probably of even greater importance for the effective containment of these pandrug- resistant strains. S18 ESBL-producing Escherichia coli in the UK N. Woodford ° (...
Mouth care should always finish with a lip moisturizer such as vaseline or an antibiotic prescription gel which may be applied with a soft sponge. To remove secretions around the ET tube cuff, where most of the micro-aspirations occur, use a soft oropharyngeal catheter which is specifically desi...
Treatment with recombinant human deoxyribonuclease (rhDNase) effectively reduced NET formation, particularly when combined with antibiotic therapy, thereby partially alleviating organ damage. Furthermore, administration of DNase to improved survival rates, and these experiments provided evidence that delayed ...
Innoviva Specialty Therapeutics, Inc., a subsidiary of Innoviva, Inc., announced that positive results from the Phase 3 oral zoliflodacin trial will be highlighted in an oral presentation given by the Global Antibiotic Research...
Others studies have demonstrated a "protective" role for streptococci in the oral cavity. Hydrogen peroxide-producing streptococci were shown to inhibit the growth of pathogenic microorganisms, including the nosocomial pathogens methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa36. ...
The present invention provides a pharmaceutical composition suitable for oral delivery including: at least one antibiotic or antiviral compound classified as BCS Class II, BCS Class III or BCS Class IV; lauroyl-carnitine; citric acid; and sodium citrate, wherein the composition is buffered at pH ...
Current treatment for bacterial conjunctivitis is topical antibiotic in the form of eyedrops or an ointment. There is no treatment for viral conjunctivitis; it must simply run its course.Vaginitis, sinusitis, urethritis, urinary tract and conjunctivitis infections can manifest as a biofilm. Biofilms...