restrictions imposed to ODS in a broader sense; these often make reference to imports of MB and may require specific permits (from the Ministry of the Environment Ozone Unit, the Ministry of Agriculture Pesticides Division or both) and even official supervision. multilateralfund.org 其他国家也有...
and new tailing pond) and applications for the transfer, obtained or renewal of certain certificates and licenses from Shangma Iron Mine to Fushun Shangma, Fushun Shangma has obtain all the material licenses, certificates, approval and permits which are necessary for its business operation activities...
What is the reason for the contradictory role that the SOX family may play in the same downstream signaling pathway in different or even the same tumors? The vast majority of research has focused on the three members of SOX2, SOX4, and SOX9. Do other members, particularly those in the sam...
Treatment of relapsed and/or refractory multiple myeloma (RRMM) utilizing the novel therapeutic target of the B-cell maturation antigen (BCMA) has demonstrated incredible results, leading to regulatory approval of BCMA-targeted chimeric antigen receptor (CAR)-T cell therapies in RRMM. With now two...
[81]. The combination of metformin with PD-1 blockade enhanced intratumor T cell activation and proliferation, leading to tumor clearance. This observation suggests that non-responders to PD-1 antibodies may have high mROS and more hypoxic microenvironment, which results in compromised T cell ...
Peripheral nerve injuries and central neurologic conditions can result in extensive disabilities. In cases with unilateral impairment, assessing the asymmetry between the upper extremity has been used to assess outcomes of treatment and severity of injur
Results of the CARTITUDE-1 trials showed that for a single cilta-cel infusion of 0.75 × 106 CARs pe kg, the anti-tumor effect is significant. Thus, the OS was 97%, with 67% achieving CR. The anti-tumor effect was fast as the median time to first response was one month follo...
The Steinberg and Venzon approach permits the researcher to select one among a number of different treatment arms as being worthy of further evaluation in a subsequent study. This method requires an adequate gap in the number of immune responses among different arms be observed in order to limit...
This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 12 Sergey G. Ermilov ...
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