The basic principle behind optical tweezers is the momentum transfer associated with bending light. Light carries momentum that is proportional to its energy and in the direction of propagation. Any change in the direction of light, by reflection or refraction, will result in a change of the ...
Figure 1: Schematic diagrams of various optical tweezers. (a) Single-beam optical tweezers, (b) holographic optical tweezers and (c) TOMOTRAP employing real-time 3D refractive index tomography and wavefront shaping. The 3D beam intensity generated by each of the optical tweezers is depicted on ...
Standard optical tweezers rely on optical forces arising when a focused laser beam interacts with a microscopic particle: scattering forces, pushing the particle along the beam direction, and gradient forces, attracting it towards the high-intensity focal spot. Importantly, the incoming laser beam is...
Optical tweezers is increasingly being used in bio-assays as it provides a means to observe bio-molecules non invasively and offers a spatial resolution in nanometers and force resolution in femto-Newtons at millisecond timescales.In this work, physics governing the operating principle behind optical...
Optical tweezers are a promising tool for nan... NG Dagalakis,T Lebrun,J Lippiatt - IEEE-NANO IEEE Conference on Nanotechnology 被引量: 27发表: 2002年 The Development and Application of Optical Tweezer The principle,key parameters and system setup of optical tweezer were introduced.The ...
Optical tweezers are a versatile way to trap and manipulate particles and untethered biological cells, exploiting the intensity gradients that can be created by focused lasers. One problem, however, has always been the potential for the material being manipulated to suffer thermal damage or overheating...
The scanning probe microscopes, the scanning near-field optical microscope, the optical tweezers and their applications are introduced. 本文讨论了测量和控制生物大分子的技术 ,介绍了扫描探针显微镜、扫描近场光学显微镜和光镊等以及它们的应用。 更多例句>> 4...
Since the time of their introduction, optical tweezers (OTs) have grown to be a powerful tool in the hands of biologists. OTs use highly focused laser light to guide, manipulate, or sort target objects, typically in the nanoscale to microscale range. OTs have been particularly useful in makin...
cell clusters reaching mm-size, optical trapping would lead to over-heating due to the intensities needed to counteract the growing weight7, even in the most favorable case of counter-propagating optical beams creating a trapping region between two laser spots, as in the macro-tweezers system8....
1b]. Additional single cell chambers (trap and pillar-based locations) are also on the biochip to facilitate a sub-population of cells to be selected (via optical tweezers) and further single cell assays. Finally, a disc for holding three biochips and for mounting onto the centrifugal test ...