C Control response (grey) scaled by a factor of 1.79 demonstrating the same time-course as the response during activation of ChrimsonR (purple). D An example of the responses of PCs when optogenetically activating PV interneurons. Left: average responses from two fields of view recorded from ...
To test how over-activating PV interneurons in this way impacted on the activity of PCs expressing GCaMP6f we used interleaved trials of the stimulus with and without simultaneous co-activation of ChrimsonR (Fig. S8A, B). Averaged responses in 4 NATURE COMMUNICATIONS | (2022)13:1031 | ...