This cohort study evaluates the association between opioid dose trajectory and mortality, opioid use disorder, continued opioid therapy, and health plan
including opioid use disorder (OUD). Striatal subregions are divided based on neuroanatomy, each with unique roles in OUD. In OUD, the dorsal striatum is involved in altered reward processing, formation of habits, and development of
4 and requiring use of Prescription Drug Monitoring Programs (PDMPs).5 Given tighter regulation, it has become somewhat more difficult for persons with opioid use disorder to obtain opioids in the absence of a legitimate medical need.6 Gabapentin, a structural analog of gamma-aminobutyric acid ...
these maintenance treatments are effective in reducing opiate use, dangerous behavior, and criminal activity, while improving the mental health of patients.6,7 However, the majority of opiate-dependent individuals remain out of treatment, and those who remain in treatment exhibit only 60%...
Background and aim Opioid analgesics are often effective for pain management, but may cause constipation. The aim of this study was to determine healthcare resource use and costs in non-cancer and cancer patients with opioid-induced constipation (OIC). M
Conrad5 finds evidence of economic medicalization in numerous cases, such as male disorders associated with aging, including andropause, baldness, and erectile dysfunction; behavioral disorders such as attention deficit/hyperactivity disorder in adults and hyperactivity in children; and certain applications ...
4 and requiring use of Prescription Drug Monitoring Programs (PDMPs).5 Given tighter regulation, it has become somewhat more difficult for persons with opioid use disorder to obtain opioids in the absence of a legitimate medical need.6 Gabapentin, a structural analog of gamma-aminobutyric acid ...
Conrad5 finds evidence of economic medicalization in numerous cases, such as male disorders associated with aging, including andropause, baldness, and erectile dysfunction; behavioral disorders such as attention deficit/hyperactivity disorder in adults and hyperactivity in children; and certain applications ...
Introduction Adolescence is a key period for the initiation of alcohol use [1] and the beginning of the development of alcohol use disorder (AUD) [2]. Approximately 58% of teenagers report having at least one alcoholic drink prior to reaching 18 years of age [3]. Moreover, about 4.7% ...