A new method to validate the translation of upstream open reading frames reveals their function during the integrated stress response. Eytan Zlotorynski Research Highlights10 Feb 2016Nature Reviews Molecular Cell Biology Volume: 17, P: 136
Willis, A perspective on mammalian upstream open reading frame function, Int. J. Biochem. Cell Biol. 45 (2013) 1690-1700.Somers J, Poyry T, Willis AE. 2013. A perspective on mammalian upstream open reading frame function. Int J Biochem Cell Biol 45: 1690-1700....
A technique to probe the translation of a specific open reading frame (ORF), whereby a reporter sequence without a start codon is cloned in-frame with the assessed ORF. Helix–loop–helix (HLH). A DNA-binding domain that characterizes members of a transcription factor family. It is composed...
Such an association or the precise function of these proteins, however, remains to be experimentally determined. View article Chemokine receptors Richard Horuk, in Cytokine & Growth Factor Reviews, 2001 The open reading frame of CCR6 is on two exons and predicts a polypeptide of 368 or 374 ...
“SEQSHOWORFS “ Function from Bioinformatics toolbox and got the following error : “SEQSHOWORFS can only display at most 1000000 symbols. Use “SEQTOOL” to display ORFs for long sequences or use a shorter sub- sequence or fewer reading frames”. Since “SEQtool” is only ORF visualizatio...
Higher-order structures in the 5' untranslated region (UTR) of plus-strand RNA viruses are known in many cases to function as cis-acting elements in RNA tr... Raman,Sharmila,Bouma,... - 《Journal of Virology》 被引量: 118发表: 2003年 An accessory open reading frame (orf-x) of jaagsi...
The function of the gene products is not known. It is of interest to note that (i) the open reading frame maps entirely within the single intron of and (ii) on the basis of the extent and size of hydrophobic domains, the and gene products were predicted to be . 展开 ...
An open reading frame DNA vector is presented having a promoter- translation start region, and adjacent thereto and downstream therefrom, a first coding segment having a start codon, a second coding segment coding for detectable protein, and an insertion region between said first and second coding...
Novel Function Of Chromosome 7 Open Reading Frame 41 Gene To Promote Leukemic Megakaryocyte Differentiation By Modulating TPA-Induced MAPK/ERK, SAPK/JNK, and NF-B Signaling Sun X, Lu B, Hu B, Xiao W, Li W, Huang Z (2014) Novel function of the chromosome 7 open reading frame 41 gene ...
] or multiple control signals that function independently [7] or in a coordinated fashion [8–10]. One important translational control signal found in both prokaryotes and eukaryotes is the upstream open reading frame (uORF), a small open reading frame located upstream of the main coding region...