Peak Action Duration of Action Rapid-acting Lispro, aspart, glulisine† 5–15 minutes 45–75 minutes 3–5 hours Inhaled regular < 15 minutes 50 minutes 2–3 hours Short-acting Regular† 30–60 minutes 2–4 hours 6–8 hours Intermediate-acting ...
Medication nonadherence is one of the largest problems in healthcare today, particularly for patients undergoing long-term pharmacotherapy. To combat nonadherence, it is often recommended to prescribe so-called “forgiving” drugs, which maintain their effect despite lapses in patient adherence. Neverthele...
The benzodiazepines were found to differ with respect to onset of peak effect, duration of maximum effect, total length of action, and brain half-life. The ex vivo determination of (3H)-FNZ binding is thought measure benzodiazepine-like activity produced by the parent compound and its active ...
Wåhlin-Boll and R. Pauwels 摘要: The aim of the study was to investigate the time of onset and the duration of the bronchodilating effect of different doses of formoterol administered via Turbuhaler® in patients with moderate asthma. Thirty-one patients (five women) with a mean forced ...
Measurements of subjective near ADD and pupil diameter were made after the initial reading at 5 minutes interval for the first hour and every 30 minutes for the next 7 hours for each participant. Time of onset, time of peak cycloplegia, duration of peak cycloplegia and duration of total ...
This is based on the finding that a drug's abuse liability is related to rate of onset and duration of action, that is, the quicker the onset and offset, the higher the abuse liability (Busto and Sellers, 1986; Oldendorf, 1992; Volkow et al, 1995; Woolverton and Wang, 2004). Also...
Insulin with a rapid onset and short duration of action EMEA0.3 Chariovalda, after long sustaining the enemy's fury, cheered on his men to break by a dense formation the onset of their bands, while he himself, plunging into the thickest of the battle, fell amid a shower of darts with...
Secondary objectives also included assessing changes in muscle soreness, thoracolumbar sensitivity measured as pressure pain thresholds (PPTs), and muscle strength measured as peak torque over three days to confirm the presence and progression of DOMS. Methods Study design and setting This experimental ...
of muscle actions. The intensity and duration of exercise are also important factors in DOMS onset. Up to six hypothesised theories have been proposed for the mechanism of DOMS, namely: lactic acid, muscle spasm, connective tissue damage, muscle damage, inflammation and the enzyme efflux theories...
It is well documented in animal and human research that unaccustomed eccentric muscle action of sufficient intensity and/or duration causes disruption of c... LL Smith - 《Medicine & Science in Sports & Exercise》 被引量: 887发表: 1991年 Effect of hydrotherapy on the signs and symptoms of de...