After gaining an idea of what the CRISPR/Cas9 system does, it makes sense that scientists are trying to use this tool as a way to silence and edit genes. The system can be modified to target specific genes by creating specific sequences of gRNA. Current studies are using the system in s...
The pronuclear injection (PI) is the simplest and widely used method to generate transgenic (Tg) mice. Unfortunately, PI-based Tg mice show uncertain transgene expression due to random transgene insertion in the genome, usually with multiple copies. Thus, typically at least three or more Tg lin...
What disadvantages do scientists discuss on transgenic crop plants? What are two pros and two cons of the use of genetically-modified organisms in agriculture? Envision the future if you will for a few minutes. The field ...
Non-human primates share over 90% of DNA with humans. This genetic similarity offers comparability in research findings and explains why they are sometimes used in medical studies. Scientists made significant discoveries about diseases, disorders, prevention, and treatments for both humans and animals,...
Having key scientists researching T. gondii from across the world all in one place at the conference in Buzios sharing their knowledge and most importantly getting the perspectives of their colleagues in very different disciplines really helped to encourage “One Health” thinking and discussions on ...
What is gene sequencing? Provide an example of how gene sequencing is used by scientists studying evolution. Explain gene regulation: a. How does a gene get turned on? b. How does a gene get turned off? c. Why aren't all genes on in all cells?
While differences in D2R occupancy at clinically effective doses or polypharmacology (e.g., partial agonism of 5-HT1ARs) likely contribute to these differences, scientists at Acadia Pharmaceuticals identified functionally distinct effects at the 5-HT2AR as being, at least in part, responsible for ...
In addition to human, veterinary and environmental health specialists joining hands, we need anthropologists, chemists, ecologists, educators, engineers, private industry, social scientists, etc. to all work in interactive One Health systems and thinking. This will require conjoined concerted effort. ...
The model, successfully developed, validated, and implemented, was a product of our physician data scientists' team. A substantial need and desire for incorporating machine-learning models into everyday clinical care exists, and we aim to share our experience to encourage similar clinician-led ...
Poole, T., «Welfare considerations with regard to transgenic animals», Animal Welfare, nº 4, 1995, pp. 81-85.Welfare considerations with regard to transgenic animals - Poole - 1995 () Citation Context ...or it could be left unaffected where the modification changes only the ...